Comparative performance and health economic analysis of prenatal screening for down syndrome in Fujian province, China

Comparative performance and health economic analysis of prenatal screening for down syndrome in Fujian province, China

Abstract To compare the performance of first-trimester serum screening (FTSS) and non-invasive prenatal testing (NIPT) in detecting fetal chromosomal aneuploidies trisomy 21 (T21) and trisomy 18 (T18), and to evaluate the cost-effectiveness and clinical feasibility of four screening strategies for t...

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Bibliographic Details
Main Authors: Lin Zheng, Nuolan Yin, Meiying Wang, Hailong Huang, Shuyu Zhang, Linjuan Su, Liangpu Xu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Down syndrome
Prenatal screening
First-trimester serological screening
Noninvasive prenatal test
Cost-effectiveness analysis
Online Access:https://doi.org/10.1038/s41598-025-08592-0
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