Research progress on factors influencing suboptimal immune reconstitution in HIV infection: a systematic literature review
Acquired immunodeficiency syndrome (AIDS) is an immunodeficiency syndrome caused by infection with the human immunodeficiency virus (HIV). Currently, antiretroviral therapy (ART) is the primary method for treating and managing HIV infection. With the widespread use of ART, the HIV virus is suppresse...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Chinese Journal of Public Health
2024-12-01
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| Series: | Zhongguo gonggong weisheng |
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| Online Access: | https://www.zgggws.com/article/doi/10.11847/zgggws1145815 |
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| author | Wei CHEN Qiuyi YANG Xiaoliang ZENG |
| author_facet | Wei CHEN Qiuyi YANG Xiaoliang ZENG |
| author_sort | Wei CHEN |
| collection | DOAJ |
| description | Acquired immunodeficiency syndrome (AIDS) is an immunodeficiency syndrome caused by infection with the human immunodeficiency virus (HIV). Currently, antiretroviral therapy (ART) is the primary method for treating and managing HIV infection. With the widespread use of ART, the HIV virus is suppressed, the body′s immune function gradually recovers, and the morbidity and mortality of HIV-related diseases are significantly reduced. However, some patients still fail to restore their immune function to a normal state even after long-term, regular, and effective ART, a phenomenon known as immune non-response (INR). To date, the underlying mechanisms of INR in HIV-infected patients have not been fully elucidated, but studies have shown that multiple factors may be involved. This article reviews the influencing factors of INR through an extensive literature review to provide clinical references for improving INR in HIV/AIDS patients. |
| format | Article |
| id | doaj-art-b5e5a22e652e4a42997346eadf797cf3 |
| institution | Kabale University |
| issn | 1001-0580 |
| language | zho |
| publishDate | 2024-12-01 |
| publisher | Editorial Office of Chinese Journal of Public Health |
| record_format | Article |
| series | Zhongguo gonggong weisheng |
| spelling | doaj-art-b5e5a22e652e4a42997346eadf797cf32025-02-11T02:11:59ZzhoEditorial Office of Chinese Journal of Public HealthZhongguo gonggong weisheng1001-05802024-12-0140121526153110.11847/zgggws11458151145815Research progress on factors influencing suboptimal immune reconstitution in HIV infection: a systematic literature reviewWei CHEN0Qiuyi YANG1Xiaoliang ZENG2Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning 530028, ChinaGuangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning 530028, ChinaGuangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning 530028, ChinaAcquired immunodeficiency syndrome (AIDS) is an immunodeficiency syndrome caused by infection with the human immunodeficiency virus (HIV). Currently, antiretroviral therapy (ART) is the primary method for treating and managing HIV infection. With the widespread use of ART, the HIV virus is suppressed, the body′s immune function gradually recovers, and the morbidity and mortality of HIV-related diseases are significantly reduced. However, some patients still fail to restore their immune function to a normal state even after long-term, regular, and effective ART, a phenomenon known as immune non-response (INR). To date, the underlying mechanisms of INR in HIV-infected patients have not been fully elucidated, but studies have shown that multiple factors may be involved. This article reviews the influencing factors of INR through an extensive literature review to provide clinical references for improving INR in HIV/AIDS patients.https://www.zgggws.com/article/doi/10.11847/zgggws1145815aidshuman immunodeficiency virus (hiv)immune non-response (inr)influencing factorsr |
| spellingShingle | Wei CHEN Qiuyi YANG Xiaoliang ZENG Research progress on factors influencing suboptimal immune reconstitution in HIV infection: a systematic literature review Zhongguo gonggong weisheng aids human immunodeficiency virus (hiv) immune non-response (inr) influencing factorsr |
| title | Research progress on factors influencing suboptimal immune reconstitution in HIV infection: a systematic literature review |
| title_full | Research progress on factors influencing suboptimal immune reconstitution in HIV infection: a systematic literature review |
| title_fullStr | Research progress on factors influencing suboptimal immune reconstitution in HIV infection: a systematic literature review |
| title_full_unstemmed | Research progress on factors influencing suboptimal immune reconstitution in HIV infection: a systematic literature review |
| title_short | Research progress on factors influencing suboptimal immune reconstitution in HIV infection: a systematic literature review |
| title_sort | research progress on factors influencing suboptimal immune reconstitution in hiv infection a systematic literature review |
| topic | aids human immunodeficiency virus (hiv) immune non-response (inr) influencing factorsr |
| url | https://www.zgggws.com/article/doi/10.11847/zgggws1145815 |
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