Endobronchial valve block in the treatment of patients with destructive pulmonary tuberculosis and low adherence to therapy with anti-tuberculosis drugs and refusing to stay in hospital
The objective of the study: to analyze the efficacy of endobronchial valve block (EBV) during out-patient treatment of patients with destructive pulmonary tuberculosis who refused in-patient treatment and therapy with anti-tuberculosis drugs.Subjects and methods. Treatment outcomes of 129 patients w...
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2020-01-01
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| Series: | Туберкулез и болезни лёгких |
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| Online Access: | https://www.tibl-journal.com/jour/article/view/1369 |
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| author | P. A. Fadeev D. V. Krasnov S. V. Sklyuev N. G. Grischenko V. A. Krasnov |
| author_facet | P. A. Fadeev D. V. Krasnov S. V. Sklyuev N. G. Grischenko V. A. Krasnov |
| author_sort | P. A. Fadeev |
| collection | DOAJ |
| description | The objective of the study: to analyze the efficacy of endobronchial valve block (EBV) during out-patient treatment of patients with destructive pulmonary tuberculosis who refused in-patient treatment and therapy with anti-tuberculosis drugs.Subjects and methods. Treatment outcomes of 129 patients were randomly studied, the patients suffered from destructive pulmonary tuberculosis and demonstrated low adherence to therapy with anti-tuberculosis drugs and staying in hospital. EBV was used in one group (66 patients), and it was not used in patients from another group (63 patients). Results. The use of EBV in patients with poor adherence to inpatient treatment and chemotherapy allowed achieving sputum conversion in 36 (58.1%) patients and healing of cavities in 43 (65.2%). Among the patients in whom no EBV was used, sputum conversion was achieved in 12 (20.7%) patients (p = 0.001, χ2) and cavities were healed in 14 (22.2%) patients (p = 0.001, χ2). Efficacy and safety of EBV was demonstrated when used on the out-patient basis in the above category of patients. |
| format | Article |
| id | doaj-art-b5de65a3372c406a9140c9d1c8fe16e4 |
| institution | OA Journals |
| issn | 2075-1230 2542-1506 |
| language | Russian |
| publishDate | 2020-01-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Туберкулез и болезни лёгких |
| spelling | doaj-art-b5de65a3372c406a9140c9d1c8fe16e42025-08-20T02:16:02ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062020-01-019712465310.21292/2075-1230-2019-97-12-46-531369Endobronchial valve block in the treatment of patients with destructive pulmonary tuberculosis and low adherence to therapy with anti-tuberculosis drugs and refusing to stay in hospitalP. A. Fadeev0D. V. Krasnov1S. V. Sklyuev2N. G. Grischenko3V. A. Krasnov4Zabaykalskiy Regional Clinical Phthisiopulmonary CenterNovosibirsk Tuberculosis Research Institute; Novosibirsk State Medical UniversityNovosibirsk Tuberculosis Research Institute; Novosibirsk State Medical UniversityNovosibirsk Tuberculosis Research InstituteNovosibirsk Tuberculosis Research Institute; Novosibirsk State Medical UniversityThe objective of the study: to analyze the efficacy of endobronchial valve block (EBV) during out-patient treatment of patients with destructive pulmonary tuberculosis who refused in-patient treatment and therapy with anti-tuberculosis drugs.Subjects and methods. Treatment outcomes of 129 patients were randomly studied, the patients suffered from destructive pulmonary tuberculosis and demonstrated low adherence to therapy with anti-tuberculosis drugs and staying in hospital. EBV was used in one group (66 patients), and it was not used in patients from another group (63 patients). Results. The use of EBV in patients with poor adherence to inpatient treatment and chemotherapy allowed achieving sputum conversion in 36 (58.1%) patients and healing of cavities in 43 (65.2%). Among the patients in whom no EBV was used, sputum conversion was achieved in 12 (20.7%) patients (p = 0.001, χ2) and cavities were healed in 14 (22.2%) patients (p = 0.001, χ2). Efficacy and safety of EBV was demonstrated when used on the out-patient basis in the above category of patients.https://www.tibl-journal.com/jour/article/view/1369destructive pulmonary tuberculosislow treatment adherenceendobronchial valve block |
| spellingShingle | P. A. Fadeev D. V. Krasnov S. V. Sklyuev N. G. Grischenko V. A. Krasnov Endobronchial valve block in the treatment of patients with destructive pulmonary tuberculosis and low adherence to therapy with anti-tuberculosis drugs and refusing to stay in hospital Туберкулез и болезни лёгких destructive pulmonary tuberculosis low treatment adherence endobronchial valve block |
| title | Endobronchial valve block in the treatment of patients with destructive pulmonary tuberculosis and low adherence to therapy with anti-tuberculosis drugs and refusing to stay in hospital |
| title_full | Endobronchial valve block in the treatment of patients with destructive pulmonary tuberculosis and low adherence to therapy with anti-tuberculosis drugs and refusing to stay in hospital |
| title_fullStr | Endobronchial valve block in the treatment of patients with destructive pulmonary tuberculosis and low adherence to therapy with anti-tuberculosis drugs and refusing to stay in hospital |
| title_full_unstemmed | Endobronchial valve block in the treatment of patients with destructive pulmonary tuberculosis and low adherence to therapy with anti-tuberculosis drugs and refusing to stay in hospital |
| title_short | Endobronchial valve block in the treatment of patients with destructive pulmonary tuberculosis and low adherence to therapy with anti-tuberculosis drugs and refusing to stay in hospital |
| title_sort | endobronchial valve block in the treatment of patients with destructive pulmonary tuberculosis and low adherence to therapy with anti tuberculosis drugs and refusing to stay in hospital |
| topic | destructive pulmonary tuberculosis low treatment adherence endobronchial valve block |
| url | https://www.tibl-journal.com/jour/article/view/1369 |
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