Primitive Sca-1 Positive Bone Marrow HSC in Mouse Model of Aplastic Anemia: A Comparative Study through Flowcytometric Analysis and Scanning Electron Microscopy

Primitive Sca-1 Positive Bone Marrow HSC in Mouse Model of Aplastic Anemia: A Comparative Study through Flowcytometric Analysis and Scanning Electron Microscopy

Self-renewing Hematopoietic Stem Cells (HSCs) are responsible for reconstitution of all blood cell lineages. Sca-1 is the “stem cell antigen” marker used to identify the primitive murine HSC population, the expression of which decreases upon differentiation to other mature cell types. Sca-1+ HSCs m...

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Bibliographic Details
Main Authors: Sumanta Chatterjee, Pratima Basak, Prosun Das, Madhurima Das, Jacintha Archana Pereira, Ranjan Kumar Dutta, Malay Chaklader, Samaresh Chaudhuri, Sujata Law
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.4061/2010/614395
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