Mechanisms of cell senescence and apoptosis in cyclophosphamide-induced premature ovarian failure in rats

Abstract Background Premature ovarian failure (POF) is a clinical condition characterized by a diminished ovarian reserve occurring before the age of 40, significantly affecting female reproductive health. However, its exact pathogenesis remains unclear. This research aimed to examine the mechanisms...

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Bibliographic Details
Main Authors: Jiaqi Wu, Yanmeng Wei, Qiangli Peng, Jing Zhu, Huacong Shi, Ting Zhao, Tao Yuan
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Ovarian Research
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Online Access:https://doi.org/10.1186/s13048-025-01759-3
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