Caki-1 Spheroids as a Renal Model for Studying Free Fatty Acid-Induced Lipotoxicity
Lipotoxicity, resulting from the buildup of excess lipids in non-adipose tissues, is increasingly recognized as a major contributor to the progression of kidney disease, highlighting the need for alternative models to assess its effects on renal cells. The main aim of this study was to investigate t...
Saved in:
| Main Authors: | Dana Battle, Xiangzhe Qiu, Marilyn Alex, London Rivers, Jamie A. G. Hamilton, Shuichi Takayama, Xueying Zhao |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-02-01
|
| Series: | Cells |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4409/14/5/349 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Lipotoxicity of palmitic acid is associated with DGAT1 downregulation and abolished by PPARα activation in liver cells
by: Camilla Moliterni, et al.
Published: (2024-12-01) -
GCKIII kinases control hepatocellular lipid homeostasis via shared mode of action
by: Emmelie Cansby, et al.
Published: (2024-11-01) -
Lipotoxicity and metabolic disorders at obesity
by: V. T. Ivashkin, et al.
Published: (2010-02-01) -
Role of autophagy in lipid aggregation in lipid-induced renal tubular epithelial damage
by: WANG Rui, et al.
Published: (2016-01-01) -
Phosphatidylcholine Ameliorates Palmitic Acid‐Induced Lipotoxicity by Facilitating Endoplasmic Reticulum and Mitochondria Contacts in Intervertebral Disc Degeneration
by: Shuangshuang Tu, et al.
Published: (2025-06-01)