Aortic endograft infection with Mycobacterium bovis following intravesical BCG immunotherapy diagnosed via the Karius Test™- case report and review of literature
Bacillus Calmette-Guérin (BCG), a live attenuated form of Mycobacterium bovis, is utilized in non–muscle-invasive bladder cancer therapy. Disseminated BCG infection causing vascular graft infection is extremely rare. In this report, we review the literature and describe a rare case of aortic endogra...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
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| Series: | Annals of Vascular Surgery - Brief Reports and Innovations |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772687825000170 |
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| Summary: | Bacillus Calmette-Guérin (BCG), a live attenuated form of Mycobacterium bovis, is utilized in non–muscle-invasive bladder cancer therapy. Disseminated BCG infection causing vascular graft infection is extremely rare. In this report, we review the literature and describe a rare case of aortic endograft infection in a 72- year-old man, who underwent intravesical BCG treatment four years ago that was diagnosed utilizing next generation sequencing technique via the Karius test™ enabling earlier diagnosis and treatment start compared to conventional microbiological diagnostic tools. The morbidity and mortality from aortic graft infections remain high, therefore prompt diagnosis and multidisciplinary approach is paramount. |
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| ISSN: | 2772-6878 |