Modulation of antiviral genes by African swine fever isolates of diverse virulence

Modulation of antiviral genes by African swine fever isolates of diverse virulence

African swine fever virus (ASFV), the aetiological agent of a devastating swine disease, has developed several strategies to replicate in porcine macrophages, its main target cells. In this work, we investigated the expression of 84 antiviral genes in macrophages infected with the virulent strain 26...

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Bibliographic Details
Main Authors: Giulia Franzoni, Lorena Mura, Susanna Zinellu, Pedro J. Sanchez-Cordon, Miriam Pedrera, Silvia Dei Giudici
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Veterinary Science
Subjects:
African swine fever virus
macrophages
interferon stimulatory genes
pattern recognition receptors
cytokines
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2025.1591709/full
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