Retinal Nerve Fiber Layer Thickness in Women with Polycystic Ovary Syndrome

Aim. To compare the retinal nerve fiber layer (RNFL) thickness between women with polycystic ovary syndrome (PCOS) and healthy women. Materials and Methods. The study included 88 eyes of 44 women (group 1) with PCOS and 84 eyes of 42 healthy women (group 2). In all subjects, the RNFL and ganglion ce...

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Main Authors: Mehmet Demir, Dilek Guven, Arzu Koc, Savas Ozdemir, Efe Can
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2013/752186
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author Mehmet Demir
Dilek Guven
Arzu Koc
Savas Ozdemir
Efe Can
author_facet Mehmet Demir
Dilek Guven
Arzu Koc
Savas Ozdemir
Efe Can
author_sort Mehmet Demir
collection DOAJ
description Aim. To compare the retinal nerve fiber layer (RNFL) thickness between women with polycystic ovary syndrome (PCOS) and healthy women. Materials and Methods. The study included 88 eyes of 44 women (group 1) with PCOS and 84 eyes of 42 healthy women (group 2). In all subjects, the RNFL and ganglion cell complex (GCC) thicknesses were measured by optical coherence tomography (OCT). In addition, visual acuity (VA), intraocular pressure (IOP), refractive errors, central macular thickness (CMT), central corneal thickness (CCT), and excavation of optic disc were evaluated in all subjects. Results. Mean values of GCC, IOP, VA, CMT, CCT, and refractive errors were similar between the 2 groups. The average RNFL, superior average RNFL, and inferior average RNFL thicknesses were higher in subjects with PCOS than in healthy subjects (P=0.003, P=0.012, and P=0.009), respectively. Conclusion. The average RNFL, superior average RNFL, and inferior average RNFL thicknesses in women with PCOS were significantly higher than in healthy women.
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spelling doaj-art-b5b5f9147cde4c00ac962ff17cf34ff62025-08-20T03:20:55ZengWileyJournal of Ophthalmology2090-004X2090-00582013-01-01201310.1155/2013/752186752186Retinal Nerve Fiber Layer Thickness in Women with Polycystic Ovary SyndromeMehmet Demir0Dilek Guven1Arzu Koc2Savas Ozdemir3Efe Can4Department of Ophthalmology, Sisli Etfal Training and Research Hospital, Sisli, 34400 Istanbul, TurkeyDepartment of Ophthalmology, Sisli Etfal Training and Research Hospital, Sisli, 34400 Istanbul, TurkeyDepartment of Obstetrics and Gynecology, Sisli Etfal Training and Research Hospital, Sisli, 34400 Istanbul, TurkeyDepartment of Obstetrics and Gynecology, Sisli Etfal Training and Research Hospital, Sisli, 34400 Istanbul, TurkeyDepartment of Ophthalmology, Sisli Etfal Training and Research Hospital, Sisli, 34400 Istanbul, TurkeyAim. To compare the retinal nerve fiber layer (RNFL) thickness between women with polycystic ovary syndrome (PCOS) and healthy women. Materials and Methods. The study included 88 eyes of 44 women (group 1) with PCOS and 84 eyes of 42 healthy women (group 2). In all subjects, the RNFL and ganglion cell complex (GCC) thicknesses were measured by optical coherence tomography (OCT). In addition, visual acuity (VA), intraocular pressure (IOP), refractive errors, central macular thickness (CMT), central corneal thickness (CCT), and excavation of optic disc were evaluated in all subjects. Results. Mean values of GCC, IOP, VA, CMT, CCT, and refractive errors were similar between the 2 groups. The average RNFL, superior average RNFL, and inferior average RNFL thicknesses were higher in subjects with PCOS than in healthy subjects (P=0.003, P=0.012, and P=0.009), respectively. Conclusion. The average RNFL, superior average RNFL, and inferior average RNFL thicknesses in women with PCOS were significantly higher than in healthy women.http://dx.doi.org/10.1155/2013/752186
spellingShingle Mehmet Demir
Dilek Guven
Arzu Koc
Savas Ozdemir
Efe Can
Retinal Nerve Fiber Layer Thickness in Women with Polycystic Ovary Syndrome
Journal of Ophthalmology
title Retinal Nerve Fiber Layer Thickness in Women with Polycystic Ovary Syndrome
title_full Retinal Nerve Fiber Layer Thickness in Women with Polycystic Ovary Syndrome
title_fullStr Retinal Nerve Fiber Layer Thickness in Women with Polycystic Ovary Syndrome
title_full_unstemmed Retinal Nerve Fiber Layer Thickness in Women with Polycystic Ovary Syndrome
title_short Retinal Nerve Fiber Layer Thickness in Women with Polycystic Ovary Syndrome
title_sort retinal nerve fiber layer thickness in women with polycystic ovary syndrome
url http://dx.doi.org/10.1155/2013/752186
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AT arzukoc retinalnervefiberlayerthicknessinwomenwithpolycysticovarysyndrome
AT savasozdemir retinalnervefiberlayerthicknessinwomenwithpolycysticovarysyndrome
AT efecan retinalnervefiberlayerthicknessinwomenwithpolycysticovarysyndrome