Extensive Deep Venous Thrombosis in a Patient with Neurolept Malignant Syndrome despite Being on Prophylaxis
The risk of venous thromboembolism (VTE) in patients with Neuroleptic malignant syndrome (NMS) and those on antipsychotic medications is well established. We present here a case whereby the patient had NMS and developed extensive deep venous thrombosis (DVT) despite being on standard DVT Prophylaxis...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Psychiatry |
| Online Access: | http://dx.doi.org/10.1155/2011/258172 |
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| author | Jerrin C. Mathew Unnikrishnan Pillai Alexander Lacasse |
| author_facet | Jerrin C. Mathew Unnikrishnan Pillai Alexander Lacasse |
| author_sort | Jerrin C. Mathew |
| collection | DOAJ |
| description | The risk of venous thromboembolism (VTE) in patients with Neuroleptic malignant syndrome (NMS) and those on antipsychotic medications is well established. We present here a case whereby the patient had NMS and developed extensive deep venous thrombosis (DVT) despite being on standard DVT Prophylaxis. Our case illustrates that empiric intravenous heparin for the initial few days after the onset of NMS may be considered in those with high risk of VTE, as in such patients standard DVT prophylaxis may not be sufficient. To standardize as to which patients with NMS would be at the highest risk of VTE while on standard DVT prophylaxis, the role of a standardized scoring system and a double-blind randomized trial in the future would probably be beneficial. |
| format | Article |
| id | doaj-art-b5b2f0cf21174c1aa97ae13d426b77c8 |
| institution | OA Journals |
| issn | 2090-682X 2090-6838 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Psychiatry |
| spelling | doaj-art-b5b2f0cf21174c1aa97ae13d426b77c82025-08-20T02:23:23ZengWileyCase Reports in Psychiatry2090-682X2090-68382011-01-01201110.1155/2011/258172258172Extensive Deep Venous Thrombosis in a Patient with Neurolept Malignant Syndrome despite Being on ProphylaxisJerrin C. Mathew0Unnikrishnan Pillai1Alexander Lacasse2Department of Internal Medicine, St. Mary's Health Center, St. Louis, MO 63117, USADepartment of Internal Medicine, St. Mary's Health Center, St. Louis, MO 63117, USADepartment of Internal Medicine, St. Mary's Health Center, St. Louis, MO 63117, USAThe risk of venous thromboembolism (VTE) in patients with Neuroleptic malignant syndrome (NMS) and those on antipsychotic medications is well established. We present here a case whereby the patient had NMS and developed extensive deep venous thrombosis (DVT) despite being on standard DVT Prophylaxis. Our case illustrates that empiric intravenous heparin for the initial few days after the onset of NMS may be considered in those with high risk of VTE, as in such patients standard DVT prophylaxis may not be sufficient. To standardize as to which patients with NMS would be at the highest risk of VTE while on standard DVT prophylaxis, the role of a standardized scoring system and a double-blind randomized trial in the future would probably be beneficial.http://dx.doi.org/10.1155/2011/258172 |
| spellingShingle | Jerrin C. Mathew Unnikrishnan Pillai Alexander Lacasse Extensive Deep Venous Thrombosis in a Patient with Neurolept Malignant Syndrome despite Being on Prophylaxis Case Reports in Psychiatry |
| title | Extensive Deep Venous Thrombosis in a Patient with Neurolept Malignant Syndrome despite Being on Prophylaxis |
| title_full | Extensive Deep Venous Thrombosis in a Patient with Neurolept Malignant Syndrome despite Being on Prophylaxis |
| title_fullStr | Extensive Deep Venous Thrombosis in a Patient with Neurolept Malignant Syndrome despite Being on Prophylaxis |
| title_full_unstemmed | Extensive Deep Venous Thrombosis in a Patient with Neurolept Malignant Syndrome despite Being on Prophylaxis |
| title_short | Extensive Deep Venous Thrombosis in a Patient with Neurolept Malignant Syndrome despite Being on Prophylaxis |
| title_sort | extensive deep venous thrombosis in a patient with neurolept malignant syndrome despite being on prophylaxis |
| url | http://dx.doi.org/10.1155/2011/258172 |
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