In silico screening and experimental validation identify riboflavin as an RNA-targeted antiviral against SARS-CoV-2
Abstract This study explored drug repurposing strategies against conserved RNA structures in the SARS-CoV-2 genome to address viral mutation challenges. Conserved RNA elements were computationally identified by aligning 283 SARS-CoV-2 genomes from Korean patients. RNA secondary structures were predi...
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| Main Authors: | Chae-Hong Jeong, Yoo Jin Na, Tae Yong Kim, So Young Lee, Jungyeon Kim, Sangmi Ryou |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-16949-8 |
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