Novel radiotherapy target definition using AI-driven predictions of glioblastoma recurrence from metabolic and diffusion MRI

Novel radiotherapy target definition using AI-driven predictions of glioblastoma recurrence from metabolic and diffusion MRI

Abstract The current standard-of-care (SOC) practice for defining the clinical target volume (CTV) for radiation therapy (RT) in patients with glioblastoma still employs an isotropic 1–2 cm expansion of the T2-hyperintensity lesion, without considering the heterogeneous infiltrative nature of these...

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Bibliographic Details
Main Authors: Nate Tran, Tracy L. Luks, Yan Li, Angela Jakary, Jacob Ellison, Bo Liu, Oluwaseun Adegbite, Devika Nair, Pranav Kakhandiki, Annette M. Molinaro, Javier E. Villanueva-Meyer, Nicholas Butowski, Jennifer L. Clarke, Susan M. Chang, Steve E. Braunstein, Olivier Morin, Hui Lin, Janine M. Lupo
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-025-01861-2
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