Ectopic epipericardial fat necrosis: a case report

Abstract Background Epipericardial fat necrosis (EFN) is a rare disease in which local inflammation and necrosis occur in the adipose tissue surrounding the heart, particularly epicardial fat. Few cases of EFN in which surgical resection was performed have been reported. We report a case of EFN afte...

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Main Authors: Ryusei Yoshino, Masaki Nakatsubo, Nanami Ujiie, Akane Ito, Nana Yoshida, Naoko Aoki, Masahiro Kitada
Format: Article
Language:English
Published: Japan Surgical Society 2024-03-01
Series:Surgical Case Reports
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Online Access:https://doi.org/10.1186/s40792-024-01859-0
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author Ryusei Yoshino
Masaki Nakatsubo
Nanami Ujiie
Akane Ito
Nana Yoshida
Naoko Aoki
Masahiro Kitada
author_facet Ryusei Yoshino
Masaki Nakatsubo
Nanami Ujiie
Akane Ito
Nana Yoshida
Naoko Aoki
Masahiro Kitada
author_sort Ryusei Yoshino
collection DOAJ
description Abstract Background Epipericardial fat necrosis (EFN) is a rare disease in which local inflammation and necrosis occur in the adipose tissue surrounding the heart, particularly epicardial fat. Few cases of EFN in which surgical resection was performed have been reported. We report a case of EFN after surgical resection of a right extrapulmonary tumor, in which a malignant disease could not be excluded. Case presentation A 75-year-old male patient presented with fever and chest pain. A contrast-enhanced computed tomography scan of the chest revealed a lesion, 53 × 48 mm in size, with mixed fatty density spanning the middle and lower lobes of the right lung. Thoracic magnetic resonance imaging (MRI) revealed a mass with mixed fat and soft tissue density in the same area; the lesion was contiguous with pericardial fatty tissue. The tumor was diagnosed as a liposarcoma or teratocarcinoma based on imaging results; however, the possibility of lung cancer could not be excluded. Finally, EFN was diagnosed based on the postoperative histopathological examination. The patient underwent surgical resection of the suspected right extrapulmonary tumor. The intraoperative findings revealed a mediastinal mass contiguous with pericardial fat located between the middle and lower lobes. Intraoperative pathological examination of the lesion was performed using a needle biopsy; however, no definitive diagnosis was made. The tumor may have invaded the middle lobe of the right lung, and partial resection of the right lower lobe was performed in addition to resection of the middle lobe of the right lung. The patient was followed up every 3 months without adjuvant therapy. No recurrence was reported at 1 year after surgery. Conclusion EFN should be considered in the differential diagnosis of an extrapulmonary tumor when continuity with the pericardial space is observed on MRI or other imaging studies. Surgical resection is useful in the diagnosis and treatment of EFNs. Preoperative three-dimensional reconstructive imaging and MRI should be used to identify vascular structures and confirm the continuity of the lesion with the surrounding tissues to ensure safe and rapid tumor removal.
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spelling doaj-art-b5ab8612ea2c4ecd9c583d87ae2702b72025-08-20T03:35:58ZengJapan Surgical SocietySurgical Case Reports2198-77932024-03-011011810.1186/s40792-024-01859-0Ectopic epipericardial fat necrosis: a case reportRyusei Yoshino0Masaki Nakatsubo1Nanami Ujiie2Akane Ito3Nana Yoshida4Naoko Aoki5Masahiro Kitada6Department of Thoracic Surgery and Breast Surgery, Respiratory Center, Asahikawa Medical University HospitalDepartment of Thoracic Surgery and Breast Surgery, Respiratory Center, Asahikawa Medical University HospitalDepartment of Thoracic Surgery and Breast Surgery, Respiratory Center, Asahikawa Medical University HospitalDepartment of Thoracic Surgery and Breast Surgery, Respiratory Center, Asahikawa Medical University HospitalDepartment of Thoracic Surgery and Breast Surgery, Respiratory Center, Asahikawa Medical University HospitalDepartment of Diagnostic Pathology, Asahikawa Medical University HospitalDepartment of Thoracic Surgery and Breast Surgery, Respiratory Center, Asahikawa Medical University HospitalAbstract Background Epipericardial fat necrosis (EFN) is a rare disease in which local inflammation and necrosis occur in the adipose tissue surrounding the heart, particularly epicardial fat. Few cases of EFN in which surgical resection was performed have been reported. We report a case of EFN after surgical resection of a right extrapulmonary tumor, in which a malignant disease could not be excluded. Case presentation A 75-year-old male patient presented with fever and chest pain. A contrast-enhanced computed tomography scan of the chest revealed a lesion, 53 × 48 mm in size, with mixed fatty density spanning the middle and lower lobes of the right lung. Thoracic magnetic resonance imaging (MRI) revealed a mass with mixed fat and soft tissue density in the same area; the lesion was contiguous with pericardial fatty tissue. The tumor was diagnosed as a liposarcoma or teratocarcinoma based on imaging results; however, the possibility of lung cancer could not be excluded. Finally, EFN was diagnosed based on the postoperative histopathological examination. The patient underwent surgical resection of the suspected right extrapulmonary tumor. The intraoperative findings revealed a mediastinal mass contiguous with pericardial fat located between the middle and lower lobes. Intraoperative pathological examination of the lesion was performed using a needle biopsy; however, no definitive diagnosis was made. The tumor may have invaded the middle lobe of the right lung, and partial resection of the right lower lobe was performed in addition to resection of the middle lobe of the right lung. The patient was followed up every 3 months without adjuvant therapy. No recurrence was reported at 1 year after surgery. Conclusion EFN should be considered in the differential diagnosis of an extrapulmonary tumor when continuity with the pericardial space is observed on MRI or other imaging studies. Surgical resection is useful in the diagnosis and treatment of EFNs. Preoperative three-dimensional reconstructive imaging and MRI should be used to identify vascular structures and confirm the continuity of the lesion with the surrounding tissues to ensure safe and rapid tumor removal.https://doi.org/10.1186/s40792-024-01859-0Computed tomographyEpipericardial fat necrosisFeverMagnetic resonance imagingPain
spellingShingle Ryusei Yoshino
Masaki Nakatsubo
Nanami Ujiie
Akane Ito
Nana Yoshida
Naoko Aoki
Masahiro Kitada
Ectopic epipericardial fat necrosis: a case report
Surgical Case Reports
Computed tomography
Epipericardial fat necrosis
Fever
Magnetic resonance imaging
Pain
title Ectopic epipericardial fat necrosis: a case report
title_full Ectopic epipericardial fat necrosis: a case report
title_fullStr Ectopic epipericardial fat necrosis: a case report
title_full_unstemmed Ectopic epipericardial fat necrosis: a case report
title_short Ectopic epipericardial fat necrosis: a case report
title_sort ectopic epipericardial fat necrosis a case report
topic Computed tomography
Epipericardial fat necrosis
Fever
Magnetic resonance imaging
Pain
url https://doi.org/10.1186/s40792-024-01859-0
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AT nanamiujiie ectopicepipericardialfatnecrosisacasereport
AT akaneito ectopicepipericardialfatnecrosisacasereport
AT nanayoshida ectopicepipericardialfatnecrosisacasereport
AT naokoaoki ectopicepipericardialfatnecrosisacasereport
AT masahirokitada ectopicepipericardialfatnecrosisacasereport