Altered Cellular Distribution and Sub-Cellular Sorting of Doppel (Dpl) Protein in Human Astrocytoma Cell Lines

Doppel, a prion-like protein, is a GPI-membrane anchored protein generally not expressed in the Central Nervous System (CNS) of different mammalian species, including human. Nevertheless, in astrocytomas, a particular kind of glial tumors, the doppel encoding gene (PRND) is over-expressed and the co...

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Bibliographic Details
Main Authors: Elena Sbalchiero, Alberto Azzalin, Silvia Palumbo, Giulia Barbieri, Agustina Arias, Luca Simonelli, Luca Ferretti, Sergio Comincini
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.3233/CLO-2008-0429
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