Genetic Variability of Indels in the Prolactin and Dopamine Receptor D2 Genes and Their Association with the Yield of Allanto-Amniotic Fluid in Russian White Laying Hens
Currently, there is virtually no information on genetic factors affecting the yield of allanto-amniotic fluid, which is the raw material for the production of human and animal vaccines. Association studies including this trait are beneficial for increasing productivity of a biotechnological line of...
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Ankara University
2020-09-01
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| Series: | Journal of Agricultural Sciences |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/1262521 |
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| author | Anna A. Krutıkova Elena S. Fedorova Michael Romanov Olga İ. Stanıshevskaya Mikhail G. Smaragdov Andrei A. Kudınov Valeriy P. Terletsky Natalia V. Dementıeva Olga V. Mıtrofanova Nikolai V. Pleshanov |
| author_facet | Anna A. Krutıkova Elena S. Fedorova Michael Romanov Olga İ. Stanıshevskaya Mikhail G. Smaragdov Andrei A. Kudınov Valeriy P. Terletsky Natalia V. Dementıeva Olga V. Mıtrofanova Nikolai V. Pleshanov |
| author_sort | Anna A. Krutıkova |
| collection | DOAJ |
| description | Currently, there is virtually no information on genetic factors affecting the yield of allanto-amniotic fluid, which is the raw material for the production of human and animal vaccines. Association studies including this trait are beneficial for increasing productivity of a biotechnological line of chickens used for the production of ‘Clean Eggs’. We examined here a population of the Russian White breed for the effects of indels in the prolactin (PRL) and dopamine receptor D2 (DRD2) genes on the yield of extraembryonic fluid (YEF) and embryo weight at 12.5 days of development. A 24-bp insertion in the 5' flanking region of the PRL gene significantly (P<0.01) increases YEF in the embryos. The heterozygous embryos contained the highest YEF (9.6 mL) than that of the homozygous insertion (9.4 mL) and deletion embryos (8.4 mL). We also found a significant association (P<0.001) between the PRL genotypes and egg weight (EW). The results of the present study suggest a significant association between the PRL gene variation and quantitative traits in the Russian White chickens, contributing to a long-term programme on the effective use of the genetic potential of Russian gene pool breeds and populations of chickens. |
| format | Article |
| id | doaj-art-b5a718201e7243cfb69afb751d4bbcf5 |
| institution | DOAJ |
| issn | 1300-7580 2148-9297 |
| language | English |
| publishDate | 2020-09-01 |
| publisher | Ankara University |
| record_format | Article |
| series | Journal of Agricultural Sciences |
| spelling | doaj-art-b5a718201e7243cfb69afb751d4bbcf52025-08-20T03:03:55ZengAnkara UniversityJournal of Agricultural Sciences1300-75802148-92972020-09-0126337337910.15832/ankutbd.48356145Genetic Variability of Indels in the Prolactin and Dopamine Receptor D2 Genes and Their Association with the Yield of Allanto-Amniotic Fluid in Russian White Laying HensAnna A. Krutıkova0Elena S. Fedorova1Michael Romanov2Olga İ. Stanıshevskaya3Mikhail G. Smaragdov4Andrei A. Kudınov5Valeriy P. Terletsky6Natalia V. Dementıeva7Olga V. Mıtrofanova8Nikolai V. Pleshanov9Russian Research Institute of Farm Animal Genetics and Breeding — Branch of the L. K. Ernst Federal Science Centre for Animal HusbandryRussian Research Institute of Farm Animal Genetics and Breeding — Branch of the L. K. Ernst Federal Science Centre for Animal HusbandryUniversity of KentRussian Research Institute of Farm Animal Genetics and Breeding — Branch of the L. K. Ernst Federal Science Centre for Animal HusbandryRussian Research Institute of Farm Animal Genetics and Breeding — Branch of the L. K. Ernst Federal Science Centre for Animal HusbandryRussian Research Institute of Farm Animal Genetics and Breeding — Branch of the L. K. Ernst Federal Science Centre for Animal HusbandryRussian Research Institute of Farm Animal Genetics and Breeding — Branch of the L. K. Ernst Federal Science Centre for Animal HusbandryRussian Research Institute of Farm Animal Genetics and Breeding — Branch of the L. K. Ernst Federal Science Centre for Animal HusbandryRussian Research Institute of Farm Animal Genetics and Breeding — Branch of the L. K. Ernst Federal Science Centre for Animal HusbandryRussian Research Institute of Farm Animal Genetics and Breeding — Branch of the L. K. Ernst Federal Science Centre for Animal HusbandryCurrently, there is virtually no information on genetic factors affecting the yield of allanto-amniotic fluid, which is the raw material for the production of human and animal vaccines. Association studies including this trait are beneficial for increasing productivity of a biotechnological line of chickens used for the production of ‘Clean Eggs’. We examined here a population of the Russian White breed for the effects of indels in the prolactin (PRL) and dopamine receptor D2 (DRD2) genes on the yield of extraembryonic fluid (YEF) and embryo weight at 12.5 days of development. A 24-bp insertion in the 5' flanking region of the PRL gene significantly (P<0.01) increases YEF in the embryos. The heterozygous embryos contained the highest YEF (9.6 mL) than that of the homozygous insertion (9.4 mL) and deletion embryos (8.4 mL). We also found a significant association (P<0.001) between the PRL genotypes and egg weight (EW). The results of the present study suggest a significant association between the PRL gene variation and quantitative traits in the Russian White chickens, contributing to a long-term programme on the effective use of the genetic potential of Russian gene pool breeds and populations of chickens.https://dergipark.org.tr/tr/download/article-file/1262521chicken populationbiotechnological linecandidate genesinsertion-deletion polymorphismeconomically important traits |
| spellingShingle | Anna A. Krutıkova Elena S. Fedorova Michael Romanov Olga İ. Stanıshevskaya Mikhail G. Smaragdov Andrei A. Kudınov Valeriy P. Terletsky Natalia V. Dementıeva Olga V. Mıtrofanova Nikolai V. Pleshanov Genetic Variability of Indels in the Prolactin and Dopamine Receptor D2 Genes and Their Association with the Yield of Allanto-Amniotic Fluid in Russian White Laying Hens Journal of Agricultural Sciences chicken population biotechnological line candidate genes insertion-deletion polymorphism economically important traits |
| title | Genetic Variability of Indels in the Prolactin and Dopamine Receptor D2 Genes and Their Association with the Yield of Allanto-Amniotic Fluid in Russian White Laying Hens |
| title_full | Genetic Variability of Indels in the Prolactin and Dopamine Receptor D2 Genes and Their Association with the Yield of Allanto-Amniotic Fluid in Russian White Laying Hens |
| title_fullStr | Genetic Variability of Indels in the Prolactin and Dopamine Receptor D2 Genes and Their Association with the Yield of Allanto-Amniotic Fluid in Russian White Laying Hens |
| title_full_unstemmed | Genetic Variability of Indels in the Prolactin and Dopamine Receptor D2 Genes and Their Association with the Yield of Allanto-Amniotic Fluid in Russian White Laying Hens |
| title_short | Genetic Variability of Indels in the Prolactin and Dopamine Receptor D2 Genes and Their Association with the Yield of Allanto-Amniotic Fluid in Russian White Laying Hens |
| title_sort | genetic variability of indels in the prolactin and dopamine receptor d2 genes and their association with the yield of allanto amniotic fluid in russian white laying hens |
| topic | chicken population biotechnological line candidate genes insertion-deletion polymorphism economically important traits |
| url | https://dergipark.org.tr/tr/download/article-file/1262521 |
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