Oxytocin levels in response to CRH administration in hypopituitarism and hypothalamic damage: a randomized, crossover, placebo-controlled trial

Oxytocin levels in response to CRH administration in hypopituitarism and hypothalamic damage: a randomized, crossover, placebo-controlled trial

Abstract Increasing evidence supports the presence of oxytocin deficiency (OXT-D) in patients with hypopituitarism and hypothalamic damage (HHD), that might be associated with neuropsychological deficits and sexual dysfunction, leading to worse quality of life (QoL). Therefore, identifying a provoca...

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Bibliographic Details
Main Authors: Queralt Asla, Maite Garrido, Eulàlia Urgell, Sílvia Terzan, Alicia Santos, Mercè Fernández, Nimmy Varghese, Cihan Atila, Anna Calabrese, Betina Biagetti, Franziska Plessow, Ignasi Gich, Mirjam Christ-Crain, Anne Eckert, Susan M. Webb, Elizabeth A. Lawson, Anna Aulinas
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Arginine-vasopressin deficiency
Corticotropin-releasing hormone
Hypopituitarism
Hypothalamic damage
Oxytocin
Pituitary disease
Online Access:https://doi.org/10.1038/s41598-025-86566-y
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