Association between oral health status and frailty in older adults: a systematic review and meta-analysis

AimThis study aims to explore the association between oral health status and frailty in older adults using comprehensive and objective oral health measurement indicators.MethodThis study conducted a collection and retrieval of relevant literature in the following English databases: PubMed, Embase, C...

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Main Authors: Jingwen Huang, Yin Zhang, Min Xv, Likai Sun, Mei Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Public Health
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Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2025.1514623/full
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author Jingwen Huang
Yin Zhang
Min Xv
Likai Sun
Mei Wang
author_facet Jingwen Huang
Yin Zhang
Min Xv
Likai Sun
Mei Wang
author_sort Jingwen Huang
collection DOAJ
description AimThis study aims to explore the association between oral health status and frailty in older adults using comprehensive and objective oral health measurement indicators.MethodThis study conducted a collection and retrieval of relevant literature in the following English databases: PubMed, Embase, Cochrane Library, and Web of Science (up to July 1, 2024). After screening the literature according to the specified inclusion and exclusion criteria, the quality of the literature was assessed using the Joanna Briggs Institute critical appraisal tool and the Newcastle-Ottawa Scale. The degree of heterogeneity was then represented by the I2 statistic, and based on this result, a random-effects or fixed-effects model was determined for analysis. Odds ratios (OR)/standardized mean differences (SMD) and 95% confidence intervals were employed to identify the association between various oral health indicators and frailty. Sensitivity analysis was performed for all outcomes.ResultsA total of 28 articles were included. Number of teeth (SMD: −0.591), functional dentition (≥21 teeth) (OR: 0.236), no false teeth (OR: 0.733), ≤20 teeth/with denture (OR: 2.320), tooth brushing daily (OR: 0.562), tongue pressure/decreased tongue pressure (SMD: −0.582/OR: 1.618), occlusal force/occlusal force reduced (SMD: −0.526/OR: 1.846), oral diadochokinesis hypofunction (OR: 1.876), poor mixing ability (OR: 2.303) and oral health assessment tool scores ≥4 (OR: 2.501) were correlated with frailty in older adults.ConclusionVarious types of oral health indicators are associated with frailty in older adults. Investigating the relationship between oral health and frailty in older adults is of significant importance for preventing frailty, ensuring the quality of life for older adults, and promoting healthy longevity.Systematic review registrationPROSPERO CRD42024587687.
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spelling doaj-art-b59bbe9f84d24e1c9fd890a81b02afae2025-08-20T02:50:23ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-03-011310.3389/fpubh.2025.15146231514623Association between oral health status and frailty in older adults: a systematic review and meta-analysisJingwen Huang0Yin Zhang1Min Xv2Likai Sun3Mei Wang4Department of Nursing, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, ChinaDepartment of Nursing, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, ChinaDepartment of Hospital Infection Control, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, ChinaDepartment of Nursing, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, ChinaDepartment of Nursing, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, ChinaAimThis study aims to explore the association between oral health status and frailty in older adults using comprehensive and objective oral health measurement indicators.MethodThis study conducted a collection and retrieval of relevant literature in the following English databases: PubMed, Embase, Cochrane Library, and Web of Science (up to July 1, 2024). After screening the literature according to the specified inclusion and exclusion criteria, the quality of the literature was assessed using the Joanna Briggs Institute critical appraisal tool and the Newcastle-Ottawa Scale. The degree of heterogeneity was then represented by the I2 statistic, and based on this result, a random-effects or fixed-effects model was determined for analysis. Odds ratios (OR)/standardized mean differences (SMD) and 95% confidence intervals were employed to identify the association between various oral health indicators and frailty. Sensitivity analysis was performed for all outcomes.ResultsA total of 28 articles were included. Number of teeth (SMD: −0.591), functional dentition (≥21 teeth) (OR: 0.236), no false teeth (OR: 0.733), ≤20 teeth/with denture (OR: 2.320), tooth brushing daily (OR: 0.562), tongue pressure/decreased tongue pressure (SMD: −0.582/OR: 1.618), occlusal force/occlusal force reduced (SMD: −0.526/OR: 1.846), oral diadochokinesis hypofunction (OR: 1.876), poor mixing ability (OR: 2.303) and oral health assessment tool scores ≥4 (OR: 2.501) were correlated with frailty in older adults.ConclusionVarious types of oral health indicators are associated with frailty in older adults. Investigating the relationship between oral health and frailty in older adults is of significant importance for preventing frailty, ensuring the quality of life for older adults, and promoting healthy longevity.Systematic review registrationPROSPERO CRD42024587687.https://www.frontiersin.org/articles/10.3389/fpubh.2025.1514623/fulloral healthfrailtyolder adultsmeta-analysissystematic review
spellingShingle Jingwen Huang
Yin Zhang
Min Xv
Likai Sun
Mei Wang
Association between oral health status and frailty in older adults: a systematic review and meta-analysis
Frontiers in Public Health
oral health
frailty
older adults
meta-analysis
systematic review
title Association between oral health status and frailty in older adults: a systematic review and meta-analysis
title_full Association between oral health status and frailty in older adults: a systematic review and meta-analysis
title_fullStr Association between oral health status and frailty in older adults: a systematic review and meta-analysis
title_full_unstemmed Association between oral health status and frailty in older adults: a systematic review and meta-analysis
title_short Association between oral health status and frailty in older adults: a systematic review and meta-analysis
title_sort association between oral health status and frailty in older adults a systematic review and meta analysis
topic oral health
frailty
older adults
meta-analysis
systematic review
url https://www.frontiersin.org/articles/10.3389/fpubh.2025.1514623/full
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