Experimental infections with Zika virus strains reveal high vector competence of Aedes albopictus and Aedes aegypti populations from Gabon (Central Africa) for the African virus lineage
The two main Zika virus (ZIKV) vectors, Aedes albopictus and Aedes aegypti (invasive and native species, respectively), are present in Gabon (Central Africa). The aim of this study was to determine the entomological ZIKV risk associated with these mosquito species in Gabon by evaluating their vector...
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Taylor & Francis Group
2021-01-01
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| Series: | Emerging Microbes and Infections |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/22221751.2021.1939167 |
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| author | Davy Jiolle Isabelle Moltini-Conclois Judicaël Obame-Nkoghe Patrick Yangari Angélique Porciani Bethsabée Scheid Pierre Kengne Diego Ayala Anna-Bella Failloux Christophe Paupy |
| author_facet | Davy Jiolle Isabelle Moltini-Conclois Judicaël Obame-Nkoghe Patrick Yangari Angélique Porciani Bethsabée Scheid Pierre Kengne Diego Ayala Anna-Bella Failloux Christophe Paupy |
| author_sort | Davy Jiolle |
| collection | DOAJ |
| description | The two main Zika virus (ZIKV) vectors, Aedes albopictus and Aedes aegypti (invasive and native species, respectively), are present in Gabon (Central Africa). The aim of this study was to determine the entomological ZIKV risk associated with these mosquito species in Gabon by evaluating their vector competence for an African (i.e. representative of the endemic strains circulating in sub-Saharan Africa) and two Asian (i.e. representatives of exogenous epidemic strains that could be introduced) ZIKV strains. The transmission efficiency of one Ae. aegypti and two Ae. albopictus field-collected populations from Libreville and Franceville was assayed at day 7, 14 and 21 after experimental oral infection. The two mosquito species could transmit all three ZIKV strains already at day 7 post-infection, but transmission efficiency was higher for the African strain than the non-African strains (>60% versus <14%; incubation period of 14–21 days). The two mosquito species exhibited comparable vector competence for ZIKV, although the amount of viral particles (African strain) in saliva was significantly higher in Ae. albopictus than Ae. aegypti at day 14 post-infection. These findings suggest that overall, ZIKV risk in Gabon is mainly related to virus strains that circulate endemically across sub-Saharan Africa, although the transmission of non-African strains remain possible in case of introduction. Due to its high infestation indexes and ecological/geographical ranges, this risk appears mainly associated with Ae. albopictus. Vector surveillance and control methods against this invasive mosquito must be strengthened in the region to limit the risk of future outbreaks. |
| format | Article |
| id | doaj-art-b59691a3e4c54d779e20c8c0179522e7 |
| institution | Kabale University |
| issn | 2222-1751 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Emerging Microbes and Infections |
| spelling | doaj-art-b59691a3e4c54d779e20c8c0179522e72025-08-20T03:52:57ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512021-01-011011244125310.1080/22221751.2021.1939167Experimental infections with Zika virus strains reveal high vector competence of Aedes albopictus and Aedes aegypti populations from Gabon (Central Africa) for the African virus lineageDavy Jiolle0Isabelle Moltini-Conclois1Judicaël Obame-Nkoghe2Patrick Yangari3Angélique Porciani4Bethsabée Scheid5Pierre Kengne6Diego Ayala7Anna-Bella Failloux8Christophe Paupy9MIVEGEC Laboratory, Montpellier University, IRD, CNRS, Montpellier, FranceMIVEGEC Laboratory, Montpellier University, IRD, CNRS, Montpellier, FranceEcologie des Systèmes Vectoriels, Centre Interdisciplinaire de Recherches Médicales de Franceville, Franceville, GabonEcologie des Systèmes Vectoriels, Centre Interdisciplinaire de Recherches Médicales de Franceville, Franceville, GabonMIVEGEC Laboratory, Montpellier University, IRD, CNRS, Montpellier, FranceMIVEGEC Laboratory, Montpellier University, IRD, CNRS, Montpellier, FranceMIVEGEC Laboratory, Montpellier University, IRD, CNRS, Montpellier, FranceMIVEGEC Laboratory, Montpellier University, IRD, CNRS, Montpellier, FranceArboviruses and Insect Vectors Unit, Institut Pasteur, Paris, FranceMIVEGEC Laboratory, Montpellier University, IRD, CNRS, Montpellier, FranceThe two main Zika virus (ZIKV) vectors, Aedes albopictus and Aedes aegypti (invasive and native species, respectively), are present in Gabon (Central Africa). The aim of this study was to determine the entomological ZIKV risk associated with these mosquito species in Gabon by evaluating their vector competence for an African (i.e. representative of the endemic strains circulating in sub-Saharan Africa) and two Asian (i.e. representatives of exogenous epidemic strains that could be introduced) ZIKV strains. The transmission efficiency of one Ae. aegypti and two Ae. albopictus field-collected populations from Libreville and Franceville was assayed at day 7, 14 and 21 after experimental oral infection. The two mosquito species could transmit all three ZIKV strains already at day 7 post-infection, but transmission efficiency was higher for the African strain than the non-African strains (>60% versus <14%; incubation period of 14–21 days). The two mosquito species exhibited comparable vector competence for ZIKV, although the amount of viral particles (African strain) in saliva was significantly higher in Ae. albopictus than Ae. aegypti at day 14 post-infection. These findings suggest that overall, ZIKV risk in Gabon is mainly related to virus strains that circulate endemically across sub-Saharan Africa, although the transmission of non-African strains remain possible in case of introduction. Due to its high infestation indexes and ecological/geographical ranges, this risk appears mainly associated with Ae. albopictus. Vector surveillance and control methods against this invasive mosquito must be strengthened in the region to limit the risk of future outbreaks.https://www.tandfonline.com/doi/10.1080/22221751.2021.1939167Zika virusAfrican and Asian lineagesAedes aegyptiAedes albopictusGabon |
| spellingShingle | Davy Jiolle Isabelle Moltini-Conclois Judicaël Obame-Nkoghe Patrick Yangari Angélique Porciani Bethsabée Scheid Pierre Kengne Diego Ayala Anna-Bella Failloux Christophe Paupy Experimental infections with Zika virus strains reveal high vector competence of Aedes albopictus and Aedes aegypti populations from Gabon (Central Africa) for the African virus lineage Emerging Microbes and Infections Zika virus African and Asian lineages Aedes aegypti Aedes albopictus Gabon |
| title | Experimental infections with Zika virus strains reveal high vector competence of Aedes albopictus and Aedes aegypti populations from Gabon (Central Africa) for the African virus lineage |
| title_full | Experimental infections with Zika virus strains reveal high vector competence of Aedes albopictus and Aedes aegypti populations from Gabon (Central Africa) for the African virus lineage |
| title_fullStr | Experimental infections with Zika virus strains reveal high vector competence of Aedes albopictus and Aedes aegypti populations from Gabon (Central Africa) for the African virus lineage |
| title_full_unstemmed | Experimental infections with Zika virus strains reveal high vector competence of Aedes albopictus and Aedes aegypti populations from Gabon (Central Africa) for the African virus lineage |
| title_short | Experimental infections with Zika virus strains reveal high vector competence of Aedes albopictus and Aedes aegypti populations from Gabon (Central Africa) for the African virus lineage |
| title_sort | experimental infections with zika virus strains reveal high vector competence of aedes albopictus and aedes aegypti populations from gabon central africa for the african virus lineage |
| topic | Zika virus African and Asian lineages Aedes aegypti Aedes albopictus Gabon |
| url | https://www.tandfonline.com/doi/10.1080/22221751.2021.1939167 |
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