Characteristics of BCR::ABL1 kinase domain mutations in Vietnamese chronic myeloid leukemia patients

Characteristics of BCR::ABL1 kinase domain mutations in Vietnamese chronic myeloid leukemia patients

Background: BCR::ABL1 kinase domain (KD) mutations represent a common cause of resistance to tyrosine kinase inhibitors in chronic myeloid leukemia (CML) patients. The frequency and pattern of KD mutations differ among populations worldwide. However, the characteristics of KD mutations in Vietnamese...

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Main Authors: Phu Chi Dung, Huynh Duc Vinh Phu, Cao Van Dong, Chau Thuy Ha, Nguyen Thi Thanh Ha, Tran Ngoc Xuan Thy, Le Vu Ha Thanh, Huynh Nghia, Nguyen Tan Binh, Hoang Anh Vu, Phan Thi Xinh, Cao Sy Luan
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Leukemia Research Reports
Subjects:
BCR::ABL1
Kinase domain mutation
Chronic myeloid leukemia
Imatinib resistance
Vietnamese patients
Online Access:http://www.sciencedirect.com/science/article/pii/S2213048925000147
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