A New Ritodrine Selective Electrode and its Pharmaceutical Application
A novel ritodrine hydrochloride ion-selective PVC membrane electrode based on ion-pair complex of ritodrine-tetra phenyl borate was prepared with di-n-butyl phosphate as a plasticizer. The influences of membrane composition, temperature, pH of the test solution and foreign ions on the electrode perf...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2010/102162 |
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| _version_ | 1850159737057837056 |
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| author | Reda Ammar |
| author_facet | Reda Ammar |
| author_sort | Reda Ammar |
| collection | DOAJ |
| description | A novel ritodrine hydrochloride ion-selective PVC membrane electrode based on ion-pair complex of ritodrine-tetra phenyl borate was prepared with di-n-butyl phosphate as a plasticizer. The influences of membrane composition, temperature, pH of the test solution and foreign ions on the electrode performance were investigated. The electrode showed a Nernstian response over a wide ritodrine concentration range (1×10−5- 1×10−2 M) with a slope of 59.33 mV decade−1 and was found to be very selective, precise and usable within the pH range 3-7.5. The standard electrode potentials, E°, were determined at different temperatures and used to calculate the isothermal temperature coefficient (dE°/dT) of the electrode, which was 0.00075. The electrode was successfully used for potentiometric determination of ritodrine hydrochloride both in pure solutions and in pharmaceutical preparations. |
| format | Article |
| id | doaj-art-b58cf80aa5b64e4c96a53dbdfb172314 |
| institution | OA Journals |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-b58cf80aa5b64e4c96a53dbdfb1723142025-08-20T02:23:24ZengWileyE-Journal of Chemistry0973-49452090-98102010-01-017S1S103S11010.1155/2010/102162A New Ritodrine Selective Electrode and its Pharmaceutical ApplicationReda Ammar0Department of Chemistry , Faculty of Science, King Saud University, Riyadh, Saudi ArabiaA novel ritodrine hydrochloride ion-selective PVC membrane electrode based on ion-pair complex of ritodrine-tetra phenyl borate was prepared with di-n-butyl phosphate as a plasticizer. The influences of membrane composition, temperature, pH of the test solution and foreign ions on the electrode performance were investigated. The electrode showed a Nernstian response over a wide ritodrine concentration range (1×10−5- 1×10−2 M) with a slope of 59.33 mV decade−1 and was found to be very selective, precise and usable within the pH range 3-7.5. The standard electrode potentials, E°, were determined at different temperatures and used to calculate the isothermal temperature coefficient (dE°/dT) of the electrode, which was 0.00075. The electrode was successfully used for potentiometric determination of ritodrine hydrochloride both in pure solutions and in pharmaceutical preparations.http://dx.doi.org/10.1155/2010/102162 |
| spellingShingle | Reda Ammar A New Ritodrine Selective Electrode and its Pharmaceutical Application E-Journal of Chemistry |
| title | A New Ritodrine Selective Electrode and its Pharmaceutical Application |
| title_full | A New Ritodrine Selective Electrode and its Pharmaceutical Application |
| title_fullStr | A New Ritodrine Selective Electrode and its Pharmaceutical Application |
| title_full_unstemmed | A New Ritodrine Selective Electrode and its Pharmaceutical Application |
| title_short | A New Ritodrine Selective Electrode and its Pharmaceutical Application |
| title_sort | new ritodrine selective electrode and its pharmaceutical application |
| url | http://dx.doi.org/10.1155/2010/102162 |
| work_keys_str_mv | AT redaammar anewritodrineselectiveelectrodeanditspharmaceuticalapplication AT redaammar newritodrineselectiveelectrodeanditspharmaceuticalapplication |