Establishment of reverse genetics systems for Colorado tick fever virus.

The Colorado tick fever virus (CTFV), which has 12-segmented double-stranded RNA genomes, is a pathogenic arbovirus that causes severe diseases in humans. However, little progress has been made in the analysis of replication mechanisms and pathogenicity. This virological constraint is due to the abs...

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Bibliographic Details
Main Authors: Shohei Minami, Ryotaro Nouda, Katsuhisa Hirai, Zelin Chen, Tomohiro Kotaki, Yuta Kanai, Takeshi Kobayashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012921
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