Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?

Abstract On 7 June, the FDA approved aducanumab, the first new drug for Alzheimer’s disease in almost 20 years—and notably, the first drug with a putative disease‐modifying mechanism for the treatment of this devastating disorder, namely the removal of β‐amyloid (or Aβ) plaques from the brain....

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Main Authors: Giovanna Lalli, Jonathan M Schott, John Hardy, Bart De Strooper
Format: Article
Language:English
Published: Springer Nature 2021-08-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.15252/emmm.202114781
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author Giovanna Lalli
Jonathan M Schott
John Hardy
Bart De Strooper
author_facet Giovanna Lalli
Jonathan M Schott
John Hardy
Bart De Strooper
author_sort Giovanna Lalli
collection DOAJ
description Abstract On 7 June, the FDA approved aducanumab, the first new drug for Alzheimer’s disease in almost 20 years—and notably, the first drug with a putative disease‐modifying mechanism for the treatment of this devastating disorder, namely the removal of β‐amyloid (or Aβ) plaques from the brain.
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institution Kabale University
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publishDate 2021-08-01
publisher Springer Nature
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spelling doaj-art-b58865ed2caa4598874cf2c4fbbe5fbf2025-08-20T03:46:21ZengSpringer NatureEMBO Molecular Medicine1757-46761757-46842021-08-011381310.15252/emmm.202114781Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?Giovanna Lalli0Jonathan M Schott1John Hardy2Bart De Strooper3UK Dementia Research Institute at UCLDementia Research Centre, UCL Queen Square Institute of NeurologyUK Dementia Research Institute at UCLUK Dementia Research Institute at UCLAbstract On 7 June, the FDA approved aducanumab, the first new drug for Alzheimer’s disease in almost 20 years—and notably, the first drug with a putative disease‐modifying mechanism for the treatment of this devastating disorder, namely the removal of β‐amyloid (or Aβ) plaques from the brain.https://doi.org/10.15252/emmm.202114781
spellingShingle Giovanna Lalli
Jonathan M Schott
John Hardy
Bart De Strooper
Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?
EMBO Molecular Medicine
title Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?
title_full Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?
title_fullStr Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?
title_full_unstemmed Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?
title_short Aducanumab: a new phase in therapeutic development for Alzheimer’s disease?
title_sort aducanumab a new phase in therapeutic development for alzheimer s disease
url https://doi.org/10.15252/emmm.202114781
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AT johnhardy aducanumabanewphaseintherapeuticdevelopmentforalzheimersdisease
AT bartdestrooper aducanumabanewphaseintherapeuticdevelopmentforalzheimersdisease