Recurrent Mitral Valve Endocarditis Caused by Streptococcus pneumoniae in a Splenectomized Host

A 72-year-old male with a remote history of splenectomy and two previous episodes of pneumococcal endocarditis of mitral valve presented with high-grade fever and confusion for 3 days. Nine months priorly, patient underwent mitral valve repair when he had the first episode of pneumococcal mitral val...

Full description

Saved in:
Bibliographic Details
Main Authors: Shikha Shrestha, JayaKrishna Chintanaboina, Samir Pancholy
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2013/929615
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832566915605725184
author Shikha Shrestha
JayaKrishna Chintanaboina
Samir Pancholy
author_facet Shikha Shrestha
JayaKrishna Chintanaboina
Samir Pancholy
author_sort Shikha Shrestha
collection DOAJ
description A 72-year-old male with a remote history of splenectomy and two previous episodes of pneumococcal endocarditis of mitral valve presented with high-grade fever and confusion for 3 days. Nine months priorly, patient underwent mitral valve repair when he had the first episode of pneumococcal mitral valve endocarditis. He received pneumococcal vaccination two years ago. On examination during this admission, he was found to be febrile (104.3 F) and confused and had a grade 2/6 systolic murmur at the apex without any radiation. Laboratory data was significant for a white blood cell count of 22,000/mm3 (normal: 4000–11000/mm3). Blood cultures (4/4 bottles) grew penicillin-sensitive Streptococcus pneumoniae. Transesophageal echocardiogram revealed small vegetation on the posterior mitral leaflet without any evidence of abscess and severe mitral regurgitation. Patient clinically responded to intravenous ceftriaxone. However, due to recurrent pneumococcal mitral valve endocarditis and severe mitral regurgitation, the patient underwent mitral valve replacement. Patient had an uneventful recovery and was discharged home. Pneumococcal endocarditis itself is being uncommon in this current, penicillin, era; our case highlights the recurrent nature of pneumococcal endocarditis in a splenectomized host and the importance of pursuing aggressive treatment options in this clinical scenario.
format Article
id doaj-art-b583c245136d4738af3c7a3964675efb
institution Kabale University
issn 2090-6625
2090-6633
language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Case Reports in Infectious Diseases
spelling doaj-art-b583c245136d4738af3c7a3964675efb2025-02-03T01:02:53ZengWileyCase Reports in Infectious Diseases2090-66252090-66332013-01-01201310.1155/2013/929615929615Recurrent Mitral Valve Endocarditis Caused by Streptococcus pneumoniae in a Splenectomized HostShikha Shrestha0JayaKrishna Chintanaboina1Samir Pancholy2Wright Center for Graduate Medical Education, 501 Madison Avenue, Scranton, PA 18510, USAWright Center for Graduate Medical Education, 501 Madison Avenue, Scranton, PA 18510, USAWright Center for Graduate Medical Education, 501 Madison Avenue, Scranton, PA 18510, USAA 72-year-old male with a remote history of splenectomy and two previous episodes of pneumococcal endocarditis of mitral valve presented with high-grade fever and confusion for 3 days. Nine months priorly, patient underwent mitral valve repair when he had the first episode of pneumococcal mitral valve endocarditis. He received pneumococcal vaccination two years ago. On examination during this admission, he was found to be febrile (104.3 F) and confused and had a grade 2/6 systolic murmur at the apex without any radiation. Laboratory data was significant for a white blood cell count of 22,000/mm3 (normal: 4000–11000/mm3). Blood cultures (4/4 bottles) grew penicillin-sensitive Streptococcus pneumoniae. Transesophageal echocardiogram revealed small vegetation on the posterior mitral leaflet without any evidence of abscess and severe mitral regurgitation. Patient clinically responded to intravenous ceftriaxone. However, due to recurrent pneumococcal mitral valve endocarditis and severe mitral regurgitation, the patient underwent mitral valve replacement. Patient had an uneventful recovery and was discharged home. Pneumococcal endocarditis itself is being uncommon in this current, penicillin, era; our case highlights the recurrent nature of pneumococcal endocarditis in a splenectomized host and the importance of pursuing aggressive treatment options in this clinical scenario.http://dx.doi.org/10.1155/2013/929615
spellingShingle Shikha Shrestha
JayaKrishna Chintanaboina
Samir Pancholy
Recurrent Mitral Valve Endocarditis Caused by Streptococcus pneumoniae in a Splenectomized Host
Case Reports in Infectious Diseases
title Recurrent Mitral Valve Endocarditis Caused by Streptococcus pneumoniae in a Splenectomized Host
title_full Recurrent Mitral Valve Endocarditis Caused by Streptococcus pneumoniae in a Splenectomized Host
title_fullStr Recurrent Mitral Valve Endocarditis Caused by Streptococcus pneumoniae in a Splenectomized Host
title_full_unstemmed Recurrent Mitral Valve Endocarditis Caused by Streptococcus pneumoniae in a Splenectomized Host
title_short Recurrent Mitral Valve Endocarditis Caused by Streptococcus pneumoniae in a Splenectomized Host
title_sort recurrent mitral valve endocarditis caused by streptococcus pneumoniae in a splenectomized host
url http://dx.doi.org/10.1155/2013/929615
work_keys_str_mv AT shikhashrestha recurrentmitralvalveendocarditiscausedbystreptococcuspneumoniaeinasplenectomizedhost
AT jayakrishnachintanaboina recurrentmitralvalveendocarditiscausedbystreptococcuspneumoniaeinasplenectomizedhost
AT samirpancholy recurrentmitralvalveendocarditiscausedbystreptococcuspneumoniaeinasplenectomizedhost