Endoscopic Approaches to the Treatment of Variceal Hemorrhage in Hemodialysis-Dependent Patients

Background. Esophagogastric variceal hemorrhage leads to challenging situation in chronic kidney disease patients on maintenance hemodialysis. Aims. To determine the safety and efficacy of endoscopic approaches to patients with hemodialysis-dependent concomitant with esophagogastric varices. Methods...

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Main Authors: Xiaoquan Huang, Lili Ma, Xiaoqing Zeng, Jian Wang, Jie Chen, Shiyao Chen
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2016/9732039
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author Xiaoquan Huang
Lili Ma
Xiaoqing Zeng
Jian Wang
Jie Chen
Shiyao Chen
author_facet Xiaoquan Huang
Lili Ma
Xiaoqing Zeng
Jian Wang
Jie Chen
Shiyao Chen
author_sort Xiaoquan Huang
collection DOAJ
description Background. Esophagogastric variceal hemorrhage leads to challenging situation in chronic kidney disease patients on maintenance hemodialysis. Aims. To determine the safety and efficacy of endoscopic approaches to patients with hemodialysis-dependent concomitant with esophagogastric varices. Methods. Medical records were reviewed from January 1, 2004, to December 31, 2015, in our hospital. Five consecutive hemodialysis-dependent patients with variceal hemorrhage who underwent endoscopic treatments were retrospectively studied. Results. The median age of the patients was 54 years (range 34–67 years) and the median follow-up period was 21.3 months (range 7–134 months). All the patients received a total of three times heparin-free hemodialysis 24 hours before and no more than 24 hours and 72 hours after endoscopic treatment. They successfully had endoscopic variceal ligation, endoscopic injection sclerotherapy, and/or N-butyl cyanoacrylate injection. The short-term efficacy is satisfying and long-term follow-up showed episodes of rebleeding. Conclusions. Endoscopic approaches are the alternative options in the treatment of upper gastroenterology variceal hemorrhage in hemodialysis-dependent patients without severe complications.
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spelling doaj-art-b580d32455174383863a8f2628ac88312025-02-03T05:53:39ZengWileyGastroenterology Research and Practice1687-61211687-630X2016-01-01201610.1155/2016/97320399732039Endoscopic Approaches to the Treatment of Variceal Hemorrhage in Hemodialysis-Dependent PatientsXiaoquan Huang0Lili Ma1Xiaoqing Zeng2Jian Wang3Jie Chen4Shiyao Chen5Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, ChinaEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, ChinaDepartment of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai 200032, ChinaDepartment of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai 200032, ChinaDepartment of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai 200032, ChinaEndoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, ChinaBackground. Esophagogastric variceal hemorrhage leads to challenging situation in chronic kidney disease patients on maintenance hemodialysis. Aims. To determine the safety and efficacy of endoscopic approaches to patients with hemodialysis-dependent concomitant with esophagogastric varices. Methods. Medical records were reviewed from January 1, 2004, to December 31, 2015, in our hospital. Five consecutive hemodialysis-dependent patients with variceal hemorrhage who underwent endoscopic treatments were retrospectively studied. Results. The median age of the patients was 54 years (range 34–67 years) and the median follow-up period was 21.3 months (range 7–134 months). All the patients received a total of three times heparin-free hemodialysis 24 hours before and no more than 24 hours and 72 hours after endoscopic treatment. They successfully had endoscopic variceal ligation, endoscopic injection sclerotherapy, and/or N-butyl cyanoacrylate injection. The short-term efficacy is satisfying and long-term follow-up showed episodes of rebleeding. Conclusions. Endoscopic approaches are the alternative options in the treatment of upper gastroenterology variceal hemorrhage in hemodialysis-dependent patients without severe complications.http://dx.doi.org/10.1155/2016/9732039
spellingShingle Xiaoquan Huang
Lili Ma
Xiaoqing Zeng
Jian Wang
Jie Chen
Shiyao Chen
Endoscopic Approaches to the Treatment of Variceal Hemorrhage in Hemodialysis-Dependent Patients
Gastroenterology Research and Practice
title Endoscopic Approaches to the Treatment of Variceal Hemorrhage in Hemodialysis-Dependent Patients
title_full Endoscopic Approaches to the Treatment of Variceal Hemorrhage in Hemodialysis-Dependent Patients
title_fullStr Endoscopic Approaches to the Treatment of Variceal Hemorrhage in Hemodialysis-Dependent Patients
title_full_unstemmed Endoscopic Approaches to the Treatment of Variceal Hemorrhage in Hemodialysis-Dependent Patients
title_short Endoscopic Approaches to the Treatment of Variceal Hemorrhage in Hemodialysis-Dependent Patients
title_sort endoscopic approaches to the treatment of variceal hemorrhage in hemodialysis dependent patients
url http://dx.doi.org/10.1155/2016/9732039
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