Patient and Provider Reported Reasons for Lost to Follow Up in MDRTB Treatment: A Qualitative Study from a Drug Resistant TB Centre in India.
<h4>Introduction</h4>Multidrug-resistant Tuberculosis (MDR TB) is emerging public health concern globally. Lost to follow-up (LTFU) is one of the key challenge in MDRTB treatment. In 2013, 18% of MDR TB patients were reported LTFU in India. A qualitative study was conducted to obtain bet...
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Public Library of Science (PLoS)
2015-01-01
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| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0135802&type=printable |
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| author | Rajesh D Deshmukh D J Dhande Kuldeep Singh Sachdeva Achuthan Sreenivas A M V Kumar Srinath Satyanarayana Malik Parmar Patrick K Moonan Terrence Q Lo |
| author_facet | Rajesh D Deshmukh D J Dhande Kuldeep Singh Sachdeva Achuthan Sreenivas A M V Kumar Srinath Satyanarayana Malik Parmar Patrick K Moonan Terrence Q Lo |
| author_sort | Rajesh D Deshmukh |
| collection | DOAJ |
| description | <h4>Introduction</h4>Multidrug-resistant Tuberculosis (MDR TB) is emerging public health concern globally. Lost to follow-up (LTFU) is one of the key challenge in MDRTB treatment. In 2013, 18% of MDR TB patients were reported LTFU in India. A qualitative study was conducted to obtain better understanding of both patient and provider related factors for LTFU among MDR TB treatment.<h4>Methods</h4>Qualitative semi-structured personal interviews were conducted with 20 MDRTB patients reported as LTFU and 10 treatment providers in seven districts linked to Nagpur Drug resistant TB Centre (DRTBC) during August 2012-February 2013. Interviews were transcribed and inductive content analysis was performed to derive emergent themes.<h4>Results</h4>We found multiple factors influencing MDR TB treatment adherence. Barriers to treatment adherence included drug side effects, a perceived lack of provider support, patient financial constraints, conflicts with the timing of treatment services, alcoholism and social stigma.<h4>Conclusions</h4>Patient adherence to treatment is multi-factorial and involves individual patient factors, provider factors, and community factors. Addressing issue of LTFU during MDRTB treatment requires enhanced efforts towards resolving medical problems like adverse drug effects, developing short duration treatment regimens, reducing pill burden, motivational counselling, flexible timings for DOT services, social, family support for patients & improving awareness about disease. |
| format | Article |
| id | doaj-art-b580cef428e84be68a8f7d61e6c1de75 |
| institution | OA Journals |
| issn | 1932-6203 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-b580cef428e84be68a8f7d61e6c1de752025-08-20T02:22:46ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01108e013580210.1371/journal.pone.0135802Patient and Provider Reported Reasons for Lost to Follow Up in MDRTB Treatment: A Qualitative Study from a Drug Resistant TB Centre in India.Rajesh D DeshmukhD J DhandeKuldeep Singh SachdevaAchuthan SreenivasA M V KumarSrinath SatyanarayanaMalik ParmarPatrick K MoonanTerrence Q Lo<h4>Introduction</h4>Multidrug-resistant Tuberculosis (MDR TB) is emerging public health concern globally. Lost to follow-up (LTFU) is one of the key challenge in MDRTB treatment. In 2013, 18% of MDR TB patients were reported LTFU in India. A qualitative study was conducted to obtain better understanding of both patient and provider related factors for LTFU among MDR TB treatment.<h4>Methods</h4>Qualitative semi-structured personal interviews were conducted with 20 MDRTB patients reported as LTFU and 10 treatment providers in seven districts linked to Nagpur Drug resistant TB Centre (DRTBC) during August 2012-February 2013. Interviews were transcribed and inductive content analysis was performed to derive emergent themes.<h4>Results</h4>We found multiple factors influencing MDR TB treatment adherence. Barriers to treatment adherence included drug side effects, a perceived lack of provider support, patient financial constraints, conflicts with the timing of treatment services, alcoholism and social stigma.<h4>Conclusions</h4>Patient adherence to treatment is multi-factorial and involves individual patient factors, provider factors, and community factors. Addressing issue of LTFU during MDRTB treatment requires enhanced efforts towards resolving medical problems like adverse drug effects, developing short duration treatment regimens, reducing pill burden, motivational counselling, flexible timings for DOT services, social, family support for patients & improving awareness about disease.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0135802&type=printable |
| spellingShingle | Rajesh D Deshmukh D J Dhande Kuldeep Singh Sachdeva Achuthan Sreenivas A M V Kumar Srinath Satyanarayana Malik Parmar Patrick K Moonan Terrence Q Lo Patient and Provider Reported Reasons for Lost to Follow Up in MDRTB Treatment: A Qualitative Study from a Drug Resistant TB Centre in India. PLoS ONE |
| title | Patient and Provider Reported Reasons for Lost to Follow Up in MDRTB Treatment: A Qualitative Study from a Drug Resistant TB Centre in India. |
| title_full | Patient and Provider Reported Reasons for Lost to Follow Up in MDRTB Treatment: A Qualitative Study from a Drug Resistant TB Centre in India. |
| title_fullStr | Patient and Provider Reported Reasons for Lost to Follow Up in MDRTB Treatment: A Qualitative Study from a Drug Resistant TB Centre in India. |
| title_full_unstemmed | Patient and Provider Reported Reasons for Lost to Follow Up in MDRTB Treatment: A Qualitative Study from a Drug Resistant TB Centre in India. |
| title_short | Patient and Provider Reported Reasons for Lost to Follow Up in MDRTB Treatment: A Qualitative Study from a Drug Resistant TB Centre in India. |
| title_sort | patient and provider reported reasons for lost to follow up in mdrtb treatment a qualitative study from a drug resistant tb centre in india |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0135802&type=printable |
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