Evaluation of ocular and cervical vestibular evoked myogenic potentials in a conductive hearing loss model

Objective: To investigate the effects of conductive hearing loss (CHL) on vestibular evoked myogenic potentials (VEMPs) using a simulated CHL model, and to provide the basis for future studies. Methods: Twenty-one healthy subjects were recruited in this study. We measured ocular VEMPs (oVEMPs) and c...

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Main Authors: Peng Han, Rui Zhang, Zichen Chen, Ying Gao, Ying Cheng, Qing Zhang, Min Xu
Format: Article
Language:English
Published: Tsinghua University Press 2016-12-01
Series:Journal of Otology
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Online Access:http://www.sciencedirect.com/science/article/pii/S1672293016300812
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author Peng Han
Rui Zhang
Zichen Chen
Ying Gao
Ying Cheng
Qing Zhang
Min Xu
author_facet Peng Han
Rui Zhang
Zichen Chen
Ying Gao
Ying Cheng
Qing Zhang
Min Xu
author_sort Peng Han
collection DOAJ
description Objective: To investigate the effects of conductive hearing loss (CHL) on vestibular evoked myogenic potentials (VEMPs) using a simulated CHL model, and to provide the basis for future studies. Methods: Twenty-one healthy subjects were recruited in this study. We measured ocular VEMPs (oVEMPs) and cervical VEMPs (cVEMPs) in these subjects by air-conduction sound (ACS) stimulation. CHL was simulated later by blocking the right external auditory canal with a soundproof earplug to evaluate its impacts on VEMPs. Subjects' responses before simulated CHL served as the control, and were compared to their responses following simulated CHL. Results: oVEMPs following simulated CHL showed decreased response rate, elevated thresholds, attenuated amplitudes and prolonged N1 latencies compared with those before simulated CHL, and the differences were statistically significant. Similarly, cVEMPs following simulated CHL also showed decreased response rate, elevated thresholds and attenuated amplitudes, with prolonged P1 latencies compared with those before simulated CHL, although only differences in response rate, threshold and amplitude were significant. Conclusions: Conductive hearing loss affects the response rate and other response parameters in oVEMPs and cVEMPs.
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series Journal of Otology
spelling doaj-art-b57e5d30c7e64517b0c3b4ebbc365dcc2025-08-20T03:49:17ZengTsinghua University PressJournal of Otology1672-29302016-12-0111419219710.1016/j.joto.2016.12.002Evaluation of ocular and cervical vestibular evoked myogenic potentials in a conductive hearing loss modelPeng Han0Rui Zhang1Zichen Chen2Ying Gao3Ying Cheng4Qing Zhang5Min Xu6Department of Otorhinolaryngology-Head and Neck Surgery, Ear Institute, Second Affiliated Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, 710004 ChinaDepartment of Otorhinolaryngology-Head and Neck Surgery, Ear Institute, Second Affiliated Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, 710004 ChinaDepartment of Otorhinolaryngology-Head and Neck Surgery, Ear Institute, Second Affiliated Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, 710004 ChinaDepartment of Otorhinolaryngology-Head and Neck Surgery, Ear Institute, Second Affiliated Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, 710004 ChinaDepartment of Otorhinolaryngology-Head and Neck Surgery, Ear Institute, Second Affiliated Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, 710004 ChinaDepartment of Otorhinolaryngology-Head and Neck Surgery, Ear Institute, Second Affiliated Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, 710004 ChinaDepartment of Otorhinolaryngology-Head and Neck Surgery, Ear Institute, Second Affiliated Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, 710004 ChinaObjective: To investigate the effects of conductive hearing loss (CHL) on vestibular evoked myogenic potentials (VEMPs) using a simulated CHL model, and to provide the basis for future studies. Methods: Twenty-one healthy subjects were recruited in this study. We measured ocular VEMPs (oVEMPs) and cervical VEMPs (cVEMPs) in these subjects by air-conduction sound (ACS) stimulation. CHL was simulated later by blocking the right external auditory canal with a soundproof earplug to evaluate its impacts on VEMPs. Subjects' responses before simulated CHL served as the control, and were compared to their responses following simulated CHL. Results: oVEMPs following simulated CHL showed decreased response rate, elevated thresholds, attenuated amplitudes and prolonged N1 latencies compared with those before simulated CHL, and the differences were statistically significant. Similarly, cVEMPs following simulated CHL also showed decreased response rate, elevated thresholds and attenuated amplitudes, with prolonged P1 latencies compared with those before simulated CHL, although only differences in response rate, threshold and amplitude were significant. Conclusions: Conductive hearing loss affects the response rate and other response parameters in oVEMPs and cVEMPs.http://www.sciencedirect.com/science/article/pii/S1672293016300812Conductive hearing lossOcular vestibular evoked myogenic potentials (oVEMPs)Cervical vestibular evoked myogenic potentials (cVEMPs)ModelVestibular function
spellingShingle Peng Han
Rui Zhang
Zichen Chen
Ying Gao
Ying Cheng
Qing Zhang
Min Xu
Evaluation of ocular and cervical vestibular evoked myogenic potentials in a conductive hearing loss model
Journal of Otology
Conductive hearing loss
Ocular vestibular evoked myogenic potentials (oVEMPs)
Cervical vestibular evoked myogenic potentials (cVEMPs)
Model
Vestibular function
title Evaluation of ocular and cervical vestibular evoked myogenic potentials in a conductive hearing loss model
title_full Evaluation of ocular and cervical vestibular evoked myogenic potentials in a conductive hearing loss model
title_fullStr Evaluation of ocular and cervical vestibular evoked myogenic potentials in a conductive hearing loss model
title_full_unstemmed Evaluation of ocular and cervical vestibular evoked myogenic potentials in a conductive hearing loss model
title_short Evaluation of ocular and cervical vestibular evoked myogenic potentials in a conductive hearing loss model
title_sort evaluation of ocular and cervical vestibular evoked myogenic potentials in a conductive hearing loss model
topic Conductive hearing loss
Ocular vestibular evoked myogenic potentials (oVEMPs)
Cervical vestibular evoked myogenic potentials (cVEMPs)
Model
Vestibular function
url http://www.sciencedirect.com/science/article/pii/S1672293016300812
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