Investigating the impact of IKZF1 SNPs rs4132601 and rs11978267 on acute lymphoblastic leukemia: a comprehensive meta-analysis

Investigating the impact of IKZF1 SNPs rs4132601 and rs11978267 on acute lymphoblastic leukemia: a comprehensive meta-analysis

Abstract Objective This meta-analysis investigates the association between acute lymphoblastic leukemia (ALL) susceptibility and IKZF1 gene SNPs. Methods Utilizing EMBASE, PubMed, and other databases, the study evaluated methodological quality through the Newcastle–Ottawa Scale (NOS) scoring and Har...

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Bibliographic Details
Main Authors: Sheena Mariam Thomas, Jethendra Kumar Muruganantham, Praveen Kumar Chandra Sekar, B. K. Iyshwarya, Ramakrishnan Veerabathiran
Format: Article
Language:English
Published: SpringerOpen 2025-04-01
Series:Journal of the Egyptian National Cancer Institute
Subjects:
Leukemias
Acute lymphoblastic leukemia
IKZF1 Gene
Single nucleotide polymorphisms
Heterogeneity
Genetic association
Online Access:https://doi.org/10.1186/s43046-025-00274-2
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