Comprehensive Review on Role of Nanoparticles in Gene Therapy
Gene therapy is a promising molecular-level treatment for a variety of ailments, including genetic problems. Nanoparticles are essential to the advancement of this treatment. The various roles that nanoparticles play in gene therapy are examined in this abstract, with special attention to their impo...
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| Format: | Article |
| Language: | English |
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EDP Sciences
2025-01-01
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| Series: | E3S Web of Conferences |
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| Online Access: | https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/19/e3sconf_icsget2025_04009.pdf |
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| author | Vediya Pratik Zalavadiya Ishita Trivedi Udit Mehta Dharmik Reddy B. Raja gopal |
| author_facet | Vediya Pratik Zalavadiya Ishita Trivedi Udit Mehta Dharmik Reddy B. Raja gopal |
| author_sort | Vediya Pratik |
| collection | DOAJ |
| description | Gene therapy is a promising molecular-level treatment for a variety of ailments, including genetic problems. Nanoparticles are essential to the advancement of this treatment. The various roles that nanoparticles play in gene therapy are examined in this abstract, with special attention to their importance in targeted medication administration, increased transfection efficiency, and regulated release of genetic material. Using nanoparticles as carriers for nucleic acids, such as DNA and RNA, is one of the main uses of these particles in gene therapy. Their small size and adaptable surface characteristics allow genetic material to be efficiently encapsulated and protected, allowing for its safe delivery to target cells. The therapeutic efficacy of gene-based therapies is increased and off-target effects are reduced because to this focused delivery. Additionally, by altering their surface to support cellular growth, nanoparticles can get past biological barriers like cell membranes. |
| format | Article |
| id | doaj-art-b5776e384b6f47e38ab01147f652789a |
| institution | DOAJ |
| issn | 2267-1242 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | E3S Web of Conferences |
| spelling | doaj-art-b5776e384b6f47e38ab01147f652789a2025-08-20T03:04:30ZengEDP SciencesE3S Web of Conferences2267-12422025-01-016190400910.1051/e3sconf/202561904009e3sconf_icsget2025_04009Comprehensive Review on Role of Nanoparticles in Gene TherapyVediya Pratik0Zalavadiya Ishita1Trivedi Udit2Mehta Dharmik3Reddy B. Raja gopal4Assistant Professor, School of Pharmacy, RK UniversityAssistant Professor, School of Pharmacy, RK UniversityAssistant Professor, School of Pharmacy, RK UniversityProfessor, School of Pharmacy, RK UniversityAssistant Professor, Department of EEE, Vardhaman College of EngineeringGene therapy is a promising molecular-level treatment for a variety of ailments, including genetic problems. Nanoparticles are essential to the advancement of this treatment. The various roles that nanoparticles play in gene therapy are examined in this abstract, with special attention to their importance in targeted medication administration, increased transfection efficiency, and regulated release of genetic material. Using nanoparticles as carriers for nucleic acids, such as DNA and RNA, is one of the main uses of these particles in gene therapy. Their small size and adaptable surface characteristics allow genetic material to be efficiently encapsulated and protected, allowing for its safe delivery to target cells. The therapeutic efficacy of gene-based therapies is increased and off-target effects are reduced because to this focused delivery. Additionally, by altering their surface to support cellular growth, nanoparticles can get past biological barriers like cell membranes.https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/19/e3sconf_icsget2025_04009.pdfgene therapynanoparticlesnucleic acidsgene based therapy |
| spellingShingle | Vediya Pratik Zalavadiya Ishita Trivedi Udit Mehta Dharmik Reddy B. Raja gopal Comprehensive Review on Role of Nanoparticles in Gene Therapy E3S Web of Conferences gene therapy nanoparticles nucleic acids gene based therapy |
| title | Comprehensive Review on Role of Nanoparticles in Gene Therapy |
| title_full | Comprehensive Review on Role of Nanoparticles in Gene Therapy |
| title_fullStr | Comprehensive Review on Role of Nanoparticles in Gene Therapy |
| title_full_unstemmed | Comprehensive Review on Role of Nanoparticles in Gene Therapy |
| title_short | Comprehensive Review on Role of Nanoparticles in Gene Therapy |
| title_sort | comprehensive review on role of nanoparticles in gene therapy |
| topic | gene therapy nanoparticles nucleic acids gene based therapy |
| url | https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/19/e3sconf_icsget2025_04009.pdf |
| work_keys_str_mv | AT vediyapratik comprehensivereviewonroleofnanoparticlesingenetherapy AT zalavadiyaishita comprehensivereviewonroleofnanoparticlesingenetherapy AT trivediudit comprehensivereviewonroleofnanoparticlesingenetherapy AT mehtadharmik comprehensivereviewonroleofnanoparticlesingenetherapy AT reddybrajagopal comprehensivereviewonroleofnanoparticlesingenetherapy |