Causal relationship between inflammatory bowel disease and sex: a Mendelian randomization study

Causal relationship between inflammatory bowel disease and sex: a Mendelian randomization study

ObjectiveThe aim of this study was to investigate the bidirectional causal relationship between sex hormones and IBD through a two-sample bidirectional Mendelian randomization (MR) study.MethodsBased on Genome-Wide Association Study (GWAS) pooled data on SHBG, total testosterone, bioavailable testos...

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Bibliographic Details
Main Authors: Kaiwen Wang, Yu Lou, Shunjie Tian, Zhihui Tao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Endocrinology
Subjects:
sex hormone
IBD
Mendelian randomization
genome-wide association
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1338701/full
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