Effect of bisphosphonate on bone microstructure, mechanical strength in osteoporotic rats by ovariectomy

Effect of bisphosphonate on bone microstructure, mechanical strength in osteoporotic rats by ovariectomy

Abstract Background Bisphosphonate (BP) can treat osteoporosis and prevent osteoporotic fractures in clinical. However, the effect of BP on microstructure and mechanical properties of cortical and trabecular bone has been taken little attention, separately. Methods In this study, BP was used to inte...

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Bibliographic Details
Main Authors: Yuzhu Wang, Zhanglin Wu, Chun Li, Chenhao Ma, Jingyang Chen, Mincong Wang, Dawei Gao, Yufeng Wu, Haibin Wang
Format: Article
Language:English
Published: BMC 2024-09-01
Series:BMC Musculoskeletal Disorders
Subjects:
Bisphosphonate
Bone microstructure
Mechanical strength
Osteoporosis
Online Access:https://doi.org/10.1186/s12891-024-07846-8
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