SARS-CoV-2 Mutations and Their Impacts on Virulence and Transmissibility of The Virus

The emergence of SARS-CoV-2 in 2019 and its rapid global spread led to infrequent problems for human society. This vast spreading and high mortality rate were related mainly to the potential of this virus to develop mutated variants. Due to the emergence of hyper mutated strains escaping from vaccin...

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Main Authors: Sajjad Bahman, Safar Farajnia, Effat Alizadeh, Hojjatollah Nozad Charoudeh, Mohammad Kazem Hosseini, Behrooz Naghili
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2024-07-01
Series:ImmunoAnalysis
Subjects:
Online Access:https://ia.tbzmed.ac.ir/PDF/ia-4-4.pdf
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author Sajjad Bahman
Safar Farajnia
Effat Alizadeh
Hojjatollah Nozad Charoudeh
Mohammad Kazem Hosseini
Behrooz Naghili
author_facet Sajjad Bahman
Safar Farajnia
Effat Alizadeh
Hojjatollah Nozad Charoudeh
Mohammad Kazem Hosseini
Behrooz Naghili
author_sort Sajjad Bahman
collection DOAJ
description The emergence of SARS-CoV-2 in 2019 and its rapid global spread led to infrequent problems for human society. This vast spreading and high mortality rate were related mainly to the potential of this virus to develop mutated variants. Due to the emergence of hyper mutated strains escaping from vaccine-induced immune responses, the pandemic is still ongoing despite the discovery of various vaccines, and there is little chance that it will be eradicated in the near future. Therefore, it is crucial to monitor covid-19 mutations globally in order to develop new control measures. The SARS-CoV-2 mutation’s emergence and molecular characteristics have been the major talking points of this article, with a focus on significant variants classified as variants of concern (VOC).
format Article
id doaj-art-b55fdb820bae4fb4afaab48c449d185e
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language English
publishDate 2024-07-01
publisher Tabriz University of Medical Sciences
record_format Article
series ImmunoAnalysis
spelling doaj-art-b55fdb820bae4fb4afaab48c449d185e2025-08-20T02:11:59ZengTabriz University of Medical SciencesImmunoAnalysis2783-25892024-07-01414410.34172/ia.4070ia-4070SARS-CoV-2 Mutations and Their Impacts on Virulence and Transmissibility of The VirusSajjad Bahman0Safar Farajnia1Effat Alizadeh2Hojjatollah Nozad Charoudeh3Mohammad Kazem Hosseini4Behrooz Naghili5Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, IranBiotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, IranStem Cell Research Center and Applied Cell Sciences Department, Tabriz University of Medical Sciences, Tabriz, IranIstanbul University, Faculty of Sciences, Molecular Biology and Genetics Department, Istanbul, TurkeyInfectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, IranThe emergence of SARS-CoV-2 in 2019 and its rapid global spread led to infrequent problems for human society. This vast spreading and high mortality rate were related mainly to the potential of this virus to develop mutated variants. Due to the emergence of hyper mutated strains escaping from vaccine-induced immune responses, the pandemic is still ongoing despite the discovery of various vaccines, and there is little chance that it will be eradicated in the near future. Therefore, it is crucial to monitor covid-19 mutations globally in order to develop new control measures. The SARS-CoV-2 mutation’s emergence and molecular characteristics have been the major talking points of this article, with a focus on significant variants classified as variants of concern (VOC).https://ia.tbzmed.ac.ir/PDF/ia-4-4.pdfsars-cov-2covid-19mutationvariant of concernomicron
spellingShingle Sajjad Bahman
Safar Farajnia
Effat Alizadeh
Hojjatollah Nozad Charoudeh
Mohammad Kazem Hosseini
Behrooz Naghili
SARS-CoV-2 Mutations and Their Impacts on Virulence and Transmissibility of The Virus
ImmunoAnalysis
sars-cov-2
covid-19
mutation
variant of concern
omicron
title SARS-CoV-2 Mutations and Their Impacts on Virulence and Transmissibility of The Virus
title_full SARS-CoV-2 Mutations and Their Impacts on Virulence and Transmissibility of The Virus
title_fullStr SARS-CoV-2 Mutations and Their Impacts on Virulence and Transmissibility of The Virus
title_full_unstemmed SARS-CoV-2 Mutations and Their Impacts on Virulence and Transmissibility of The Virus
title_short SARS-CoV-2 Mutations and Their Impacts on Virulence and Transmissibility of The Virus
title_sort sars cov 2 mutations and their impacts on virulence and transmissibility of the virus
topic sars-cov-2
covid-19
mutation
variant of concern
omicron
url https://ia.tbzmed.ac.ir/PDF/ia-4-4.pdf
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