Efficacy, safety, and tolerability of soticlestat (TAK-935) as adjunctive therapy in pediatric patients with dravet syndrome and Lennox–Gastaut syndrome: a meta-analysis of 3 randomized controlled trials

Efficacy, safety, and tolerability of soticlestat (TAK-935) as adjunctive therapy in pediatric patients with dravet syndrome and Lennox–Gastaut syndrome: a meta-analysis of 3 randomized controlled trials

PurposeTo evaluate the efficacy, safety, and tolerability of soticlestat as adjunctive therapy in pediatric patients with epileptic encephalopathies of Dravet syndrome (DS) and Lennox-Gastaut syndrome (LGS).MethodWe performed a computerized literature search of MEDLINE, EMBASE, Cochrane Library, Web...

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Bibliographic Details
Main Authors: Zhang Lanlan, Jiang Nana, Wang Chengzhong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
soticlestat
meta-analysis
DRAVET syndrome
lennox-gastaut syndrome
randomized controlled trial
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1586098/full
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