Predictors of in-hospital Mortality After Rapid Response System Activation in a Newly Established Tertiary Hospital

Objective:Rapid response systems (RRSs), which aim to prevent cardiac arrests and unexpected deaths, have been implemented across hospitals worldwide. Most studies on RRS shave evaluated the effects of its implementation on in-hospital mortality. In this study, we evaluated the predictive factors of...

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Main Authors: Büşra Tezcan, Müçteba Can, Çilem Bayındır Dicle, İbrahim Mungan, Derya Ademoğlu
Format: Article
Language:English
Published: Galenos Yayinevi 2022-09-01
Series:Türk Yoğun Bakim Derneği Dergisi
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Online Access: http://www.turkishjic.org/archives/archive-detail/article-preview/predictors-of-in-hospital-mortality-after-rapid-re/47797
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author Büşra Tezcan
Müçteba Can
Çilem Bayındır Dicle
İbrahim Mungan
Derya Ademoğlu
author_facet Büşra Tezcan
Müçteba Can
Çilem Bayındır Dicle
İbrahim Mungan
Derya Ademoğlu
author_sort Büşra Tezcan
collection DOAJ
description Objective:Rapid response systems (RRSs), which aim to prevent cardiac arrests and unexpected deaths, have been implemented across hospitals worldwide. Most studies on RRS shave evaluated the effects of its implementation on in-hospital mortality. In this study, we evaluated the predictive factors of in-hospital mortality for patients who were subjects of RRS activation in a newly established major hospital in Turkey.Materials and Methods:Data on RRS activations were reviewed from paper charts and electronic medical records between March 2019 and February 2020. The demographic characteristics of patients, time of and reasons for RRS activation, initial cardiac rhythm, heart rate, mean arterial pressure, pulse oximetry-measured blood oxygen saturation (SpO2), time of arrival of the rapid response team, red cell distribution width, platelet distribution width obtained from the first blood gas analysis and haemogram test results as well as glucose, sodium, potassium, pH, lactate, neutrophils and lymphocyte levelswere recorded. Univariate and multivariate logistic regression analyses were conducted to determine the independent predictors of in-hospital mortality.Results:A total of 531 patients were included in the analysis. Of these, 189 (35.6%) died during hospital admission. Compared with survivors, non-survivors were older (median age, 64 vs. 52 years) and more likely to be male (65.6% vs. 34.4%); be admitted for cardiovascular, pulmonary and oncologic diseases and trigger RRS at nightand weekends than during the day. Activation of RRS by respiratory and haemodynamic triggers as well as during nighttime and weekend hours oncologic reasons for hospital admission, low SpO2 levels, high neutrophil-to-lymphocyte ratio (NLR), potassium levels and lactate levels were predictive of in-hospital mortality.Conclusion:This study found some weaknesses in the current RRS of the hospital. Hospital staffs working overnight and on weekends should be trained and empowered. SpO2, potassium and lactate levels as well as NLR are predictors of in-hospital mortality and can guide triage decision making, which is usually a challenging and stressful task.
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language English
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publisher Galenos Yayinevi
record_format Article
series Türk Yoğun Bakim Derneği Dergisi
spelling doaj-art-b55cf8e9da2f4ad898cd0e7023edd5ec2025-08-20T03:39:28ZengGalenos YayineviTürk Yoğun Bakim Derneği Dergisi2146-64162147-267X2022-09-0120312413110.4274/tybd.galenos.2021.7659813049054Predictors of in-hospital Mortality After Rapid Response System Activation in a Newly Established Tertiary HospitalBüşra Tezcan0Müçteba Can1Çilem Bayındır Dicle2İbrahim Mungan3Derya Ademoğlu4 Ankara City Hospital, Clinic of Intensive Care, Ankara, Turkey Ankara City Hospital, Clinic of Intensive Care, Ankara, Turkey Ankara City Hospital, Clinic of Intensive Care, Ankara, Turkey Kahramanmaraş State Hospital, Clinic of Intensive Care, Kahramanmaraş, Turkey University of Health Sciences Turkey, Başakşehir Çam and Sakura City Hospital, Clinic of Intensive Care, İstanbul, Turkey Objective:Rapid response systems (RRSs), which aim to prevent cardiac arrests and unexpected deaths, have been implemented across hospitals worldwide. Most studies on RRS shave evaluated the effects of its implementation on in-hospital mortality. In this study, we evaluated the predictive factors of in-hospital mortality for patients who were subjects of RRS activation in a newly established major hospital in Turkey.Materials and Methods:Data on RRS activations were reviewed from paper charts and electronic medical records between March 2019 and February 2020. The demographic characteristics of patients, time of and reasons for RRS activation, initial cardiac rhythm, heart rate, mean arterial pressure, pulse oximetry-measured blood oxygen saturation (SpO2), time of arrival of the rapid response team, red cell distribution width, platelet distribution width obtained from the first blood gas analysis and haemogram test results as well as glucose, sodium, potassium, pH, lactate, neutrophils and lymphocyte levelswere recorded. Univariate and multivariate logistic regression analyses were conducted to determine the independent predictors of in-hospital mortality.Results:A total of 531 patients were included in the analysis. Of these, 189 (35.6%) died during hospital admission. Compared with survivors, non-survivors were older (median age, 64 vs. 52 years) and more likely to be male (65.6% vs. 34.4%); be admitted for cardiovascular, pulmonary and oncologic diseases and trigger RRS at nightand weekends than during the day. Activation of RRS by respiratory and haemodynamic triggers as well as during nighttime and weekend hours oncologic reasons for hospital admission, low SpO2 levels, high neutrophil-to-lymphocyte ratio (NLR), potassium levels and lactate levels were predictive of in-hospital mortality.Conclusion:This study found some weaknesses in the current RRS of the hospital. Hospital staffs working overnight and on weekends should be trained and empowered. SpO2, potassium and lactate levels as well as NLR are predictors of in-hospital mortality and can guide triage decision making, which is usually a challenging and stressful task. http://www.turkishjic.org/archives/archive-detail/article-preview/predictors-of-in-hospital-mortality-after-rapid-re/47797 rapid response teamcode bluemedical emergency teampredictormortality
spellingShingle Büşra Tezcan
Müçteba Can
Çilem Bayındır Dicle
İbrahim Mungan
Derya Ademoğlu
Predictors of in-hospital Mortality After Rapid Response System Activation in a Newly Established Tertiary Hospital
Türk Yoğun Bakim Derneği Dergisi
rapid response team
code blue
medical emergency team
predictor
mortality
title Predictors of in-hospital Mortality After Rapid Response System Activation in a Newly Established Tertiary Hospital
title_full Predictors of in-hospital Mortality After Rapid Response System Activation in a Newly Established Tertiary Hospital
title_fullStr Predictors of in-hospital Mortality After Rapid Response System Activation in a Newly Established Tertiary Hospital
title_full_unstemmed Predictors of in-hospital Mortality After Rapid Response System Activation in a Newly Established Tertiary Hospital
title_short Predictors of in-hospital Mortality After Rapid Response System Activation in a Newly Established Tertiary Hospital
title_sort predictors of in hospital mortality after rapid response system activation in a newly established tertiary hospital
topic rapid response team
code blue
medical emergency team
predictor
mortality
url http://www.turkishjic.org/archives/archive-detail/article-preview/predictors-of-in-hospital-mortality-after-rapid-re/47797
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AT ibrahimmungan predictorsofinhospitalmortalityafterrapidresponsesystemactivationinanewlyestablishedtertiaryhospital
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