The role of gut microbiota and metabolomic pathways in modulating the efficacy of SSRIs for major depressive disorder

The role of gut microbiota and metabolomic pathways in modulating the efficacy of SSRIs for major depressive disorder

Abstract This study aims to explore the mechanism by which gut microbiota influences the antidepressant effects of serotonin reuptake inhibitors (SSRIs) through metabolic pathways. A total of 126 patients were analyzed for their gut microbiota and metabolomics. Patients received SSRI treatment and w...

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Bibliographic Details
Main Authors: Ying Jiang, Yucai Qu, Lingyi Shi, Mengmeng Ou, Zhiqiang Du, Zhenhe Zhou, Hongliang Zhou, Haohao Zhu
Format: Article
Language:English
Published: Nature Publishing Group 2024-12-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-024-03208-z
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