Methods for identifying health status from routinely collected health data: An overview

The use of routinely collected health data (RCD) is currently helping to accelerate publications that evaluate the effectiveness and safety of medicines and medical devices. One fundamental step in using these data is developing algorithms to identify health status for use in observational studies....

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Main Authors: Mei Liu, Ke Deng, Mingqi Wang, Qiao He, Jiayue Xu, Guowei Li, Kang Zou, Xin Sun, Wen Wang
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Integrative Medicine Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213422024000805
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author Mei Liu
Ke Deng
Mingqi Wang
Qiao He
Jiayue Xu
Guowei Li
Kang Zou
Xin Sun
Wen Wang
author_facet Mei Liu
Ke Deng
Mingqi Wang
Qiao He
Jiayue Xu
Guowei Li
Kang Zou
Xin Sun
Wen Wang
author_sort Mei Liu
collection DOAJ
description The use of routinely collected health data (RCD) is currently helping to accelerate publications that evaluate the effectiveness and safety of medicines and medical devices. One fundamental step in using these data is developing algorithms to identify health status for use in observational studies. However, the processes and methodologies for determining health status using RCD remain insufficiently understood. While most current methods rely on the World Health Organization’s International Classification of Diseases (ICD) codes, they may not be universally applicable. Although machine learning methods are promising for more accurately identifying health status, they currently remain underutilized in RCD studies. To address these significant methodological gaps, we outline key steps and methodological considerations for identifying health statuses in observational studies using RCD. This review has the potential to reinforce the credibility of findings from observational studies that use RCD.
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series Integrative Medicine Research
spelling doaj-art-b55338ea694244d2b860c83d444792e52025-08-20T02:07:17ZengElsevierIntegrative Medicine Research2213-42202025-03-0114110110010.1016/j.imr.2024.101100Methods for identifying health status from routinely collected health data: An overviewMei Liu0Ke Deng1Mingqi Wang2Qiao He3Jiayue Xu4Guowei Li5Kang Zou6Xin Sun7Wen Wang8Institute of Integrated Traditional Chinese and Western Medicine, Chinese Evidence-based Medicine and Cochrane China Center, West China Hospital, Sichuan University, Chengdu, China; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China; NMPA Key Laboratory for Real World Data Research and Evaluation in Hainan, Chengdu, China; Sichuan Center of Technology Innovation for Real World Data, Chengdu, ChinaInstitute of Integrated Traditional Chinese and Western Medicine, Chinese Evidence-based Medicine and Cochrane China Center, West China Hospital, Sichuan University, Chengdu, China; NMPA Key Laboratory for Real World Data Research and Evaluation in Hainan, Chengdu, China; Sichuan Center of Technology Innovation for Real World Data, Chengdu, ChinaInstitute of Integrated Traditional Chinese and Western Medicine, Chinese Evidence-based Medicine and Cochrane China Center, West China Hospital, Sichuan University, Chengdu, China; NMPA Key Laboratory for Real World Data Research and Evaluation in Hainan, Chengdu, China; Sichuan Center of Technology Innovation for Real World Data, Chengdu, ChinaInstitute of Integrated Traditional Chinese and Western Medicine, Chinese Evidence-based Medicine and Cochrane China Center, West China Hospital, Sichuan University, Chengdu, China; NMPA Key Laboratory for Real World Data Research and Evaluation in Hainan, Chengdu, China; Sichuan Center of Technology Innovation for Real World Data, Chengdu, ChinaInstitute of Integrated Traditional Chinese and Western Medicine, Chinese Evidence-based Medicine and Cochrane China Center, West China Hospital, Sichuan University, Chengdu, China; NMPA Key Laboratory for Real World Data Research and Evaluation in Hainan, Chengdu, China; Sichuan Center of Technology Innovation for Real World Data, Chengdu, ChinaDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada; Center for Clinical Epidemiology and Methodology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China; Biostatistics Unit, Research Institute at St. Joseph's Healthcare Hamilton, Hamilton, ON, CanadaInstitute of Integrated Traditional Chinese and Western Medicine, Chinese Evidence-based Medicine and Cochrane China Center, West China Hospital, Sichuan University, Chengdu, China; NMPA Key Laboratory for Real World Data Research and Evaluation in Hainan, Chengdu, China; Sichuan Center of Technology Innovation for Real World Data, Chengdu, ChinaInstitute of Integrated Traditional Chinese and Western Medicine, Chinese Evidence-based Medicine and Cochrane China Center, West China Hospital, Sichuan University, Chengdu, China; NMPA Key Laboratory for Real World Data Research and Evaluation in Hainan, Chengdu, China; Sichuan Center of Technology Innovation for Real World Data, Chengdu, China; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China; Corresponding authors at: Institute of Integrated Traditional Chinese and Western Medicine, Chinese Evidence-based Medicine and Cochrane China Center, West China Hospital, Sichuan University, Chengdu, China.Institute of Integrated Traditional Chinese and Western Medicine, Chinese Evidence-based Medicine and Cochrane China Center, West China Hospital, Sichuan University, Chengdu, China; NMPA Key Laboratory for Real World Data Research and Evaluation in Hainan, Chengdu, China; Sichuan Center of Technology Innovation for Real World Data, Chengdu, China; Corresponding authors at: Institute of Integrated Traditional Chinese and Western Medicine, Chinese Evidence-based Medicine and Cochrane China Center, West China Hospital, Sichuan University, Chengdu, China.The use of routinely collected health data (RCD) is currently helping to accelerate publications that evaluate the effectiveness and safety of medicines and medical devices. One fundamental step in using these data is developing algorithms to identify health status for use in observational studies. However, the processes and methodologies for determining health status using RCD remain insufficiently understood. While most current methods rely on the World Health Organization’s International Classification of Diseases (ICD) codes, they may not be universally applicable. Although machine learning methods are promising for more accurately identifying health status, they currently remain underutilized in RCD studies. To address these significant methodological gaps, we outline key steps and methodological considerations for identifying health statuses in observational studies using RCD. This review has the potential to reinforce the credibility of findings from observational studies that use RCD.http://www.sciencedirect.com/science/article/pii/S2213422024000805Routinely collected health dataHealth statusMachine learning algorithmsRule-based algorithms
spellingShingle Mei Liu
Ke Deng
Mingqi Wang
Qiao He
Jiayue Xu
Guowei Li
Kang Zou
Xin Sun
Wen Wang
Methods for identifying health status from routinely collected health data: An overview
Integrative Medicine Research
Routinely collected health data
Health status
Machine learning algorithms
Rule-based algorithms
title Methods for identifying health status from routinely collected health data: An overview
title_full Methods for identifying health status from routinely collected health data: An overview
title_fullStr Methods for identifying health status from routinely collected health data: An overview
title_full_unstemmed Methods for identifying health status from routinely collected health data: An overview
title_short Methods for identifying health status from routinely collected health data: An overview
title_sort methods for identifying health status from routinely collected health data an overview
topic Routinely collected health data
Health status
Machine learning algorithms
Rule-based algorithms
url http://www.sciencedirect.com/science/article/pii/S2213422024000805
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