ATF1 and miR-27b-3p drive intervertebral disc degeneration through the PPARG/NF-κB signaling axis
Abstract Intervertebral disc degeneration (IDD) is a primary cause of degenerative disc disease; however, the mechanisms underlying it remain unknown. Although great efforts have been made to develop new regenerative therapies, their clinical success is limited. Recent research has indicated that mi...
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| Main Authors: | Wei Guo, Kun Mu, Jing-Chao Geng, Hai-Yang Xing, Yu Dong, Wen-Dong Liu, Shuan-Chi Wang, Jia-Xiao Shi, Bao-Rui Xing, Jian-Yong Zhao, Xiao-Ming Li |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-025-08186-6 |
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