Sleep is enhanced in aged male mice that overexpress calcium/calmodulin-dependent protein kinase IV

Sleep is enhanced in aged male mice that overexpress calcium/calmodulin-dependent protein kinase IV

The dysregulation of sleep–wake patterns that occurs during aging is well documented and coincides with changes in intracellular signaling pathways that regulate sleep, such as the calcium/calmodulin-dependent protein kinase (CaMKII)/cyclic-AMP response element-binding protein (CREB) pathway. Howeve...

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Bibliographic Details
Main Authors: Sierra P. Feeney, Erin Threlfall, James M. Bilboa, Christopher C. Angelakos, Mathieu E. Wimmer, Satoshi Kida, Ted Abel, Jennifer C. Tudor
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Neuroscience
Subjects:
aging
circadian rhythms and sleep
cyclic-AMP response element binding protein
electroencephalography
memory
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1596602/full
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