Efficacy of Low‐Dose Fluconazole for Primary Prophylaxis of Invasive Candida Infections in Patients With Acute Leukemia: A Double‐Blind Randomized Clinical Trial

Efficacy of Low‐Dose Fluconazole for Primary Prophylaxis of Invasive Candida Infections in Patients With Acute Leukemia: A Double‐Blind Randomized Clinical Trial

ABSTRACT Background Invasive fungal infections (IFIs), particularly Candida infections, are a significant cause of morbidity and mortality in patients with acute leukemia. While fluconazole is widely used for prophylaxis, the optimal dosing regimen remains uncertain. This study aimed to evaluate the...

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Main Authors: Roghayeh Savary‐Kouzehkonan, Kourosh Sadeghi, Soroush Rad, Neda Alijani, Zohreh Baseri, Mohammad Vaezi, Seyed Asadollah Mousavi, Bita Shahrami
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Cancer Medicine
Subjects:
acute leukemia
antifungal prophylaxis
Candida
fluconazole
hematological malignancy
invasive fungal infection
Online Access:https://doi.org/10.1002/cam4.70837
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https://doi.org/10.1002/cam4.70837

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