Effect of ranolazine on the course of ischemic heart disease after percutaneous coronary intervention
Optimization of antiischemic therapy is necessary in many patients with stable forms of coronary heart disease after or during revascularization. From the standpoint of current guidelines, the addition of second-line drugs, in particular ranolazine, to beta-blockers and/or calcium antagonists is con...
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| Format: | Article |
| Language: | English |
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TOV Chetverta Khvylia
2020-12-01
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| Series: | Кардіохірургія та інтервенційна кардіологія |
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| Online Access: | http://www.csic.com.ua/images/pdf/2020/4-2020/effect-ranolazine-course-ischemic-heart-disease-after-percutaneous-coronary-intervention.pdf |
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| _version_ | 1832573506068414464 |
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| author | О.А. Yepanchintseva O.J. Zharinov І.V. Shklianka |
| author_facet | О.А. Yepanchintseva O.J. Zharinov І.V. Shklianka |
| author_sort | О.А. Yepanchintseva |
| collection | DOAJ |
| description | Optimization of antiischemic therapy is necessary in many patients with stable forms of coronary heart disease after or during revascularization. From the standpoint of current guidelines, the addition of second-line drugs, in particular ranolazine, to beta-blockers and/or calcium antagonists is considered during anginal attacks due to incomplete revascularization, to prevent myocardial damage during percutaneous coronary interventions, and in cases when revascularization is not possible. The results of many clinical studies have proven the antiischemic effect and safety of ranolazine after coronary artery stenting. Potential advantages of ranolazine compared with other second-line antianginal drugs are the absence of significant changes in hemodynamic parameters, good tolerability and proven antiarrhythmic effects. |
| format | Article |
| id | doaj-art-b549234e55dc49a0a09235a573cfcdbb |
| institution | Kabale University |
| issn | 2305-3127 |
| language | English |
| publishDate | 2020-12-01 |
| publisher | TOV Chetverta Khvylia |
| record_format | Article |
| series | Кардіохірургія та інтервенційна кардіологія |
| spelling | doaj-art-b549234e55dc49a0a09235a573cfcdbb2025-02-02T04:03:35ZengTOV Chetverta KhvyliaКардіохірургія та інтервенційна кардіологія2305-31272020-12-01451010.31928/2305-3127-2020.4.510Effect of ranolazine on the course of ischemic heart disease after percutaneous coronary interventionО.А. Yepanchintseva0O.J. Zharinov1І.V. Shklianka2Heart Institute, Ministry of Health of Ukraine, Kyiv, Ukraine, Shupyk National Medical Academy of Postgraduate Education, Kyiv, UkraineShupyk National Medical Academy of Postgraduate Education, Kyiv, UkraineHeart Institute, Ministry of Health of Ukraine, Kyiv, Ukraine, Shupyk National Medical Academy of Postgraduate Education, Kyiv, UkraineOptimization of antiischemic therapy is necessary in many patients with stable forms of coronary heart disease after or during revascularization. From the standpoint of current guidelines, the addition of second-line drugs, in particular ranolazine, to beta-blockers and/or calcium antagonists is considered during anginal attacks due to incomplete revascularization, to prevent myocardial damage during percutaneous coronary interventions, and in cases when revascularization is not possible. The results of many clinical studies have proven the antiischemic effect and safety of ranolazine after coronary artery stenting. Potential advantages of ranolazine compared with other second-line antianginal drugs are the absence of significant changes in hemodynamic parameters, good tolerability and proven antiarrhythmic effects.http://www.csic.com.ua/images/pdf/2020/4-2020/effect-ranolazine-course-ischemic-heart-disease-after-percutaneous-coronary-intervention.pdfchronic ischemic heart diseasepercutaneous coronary interventionranolazine |
| spellingShingle | О.А. Yepanchintseva O.J. Zharinov І.V. Shklianka Effect of ranolazine on the course of ischemic heart disease after percutaneous coronary intervention Кардіохірургія та інтервенційна кардіологія chronic ischemic heart disease percutaneous coronary intervention ranolazine |
| title | Effect of ranolazine on the course of ischemic heart disease after percutaneous coronary intervention |
| title_full | Effect of ranolazine on the course of ischemic heart disease after percutaneous coronary intervention |
| title_fullStr | Effect of ranolazine on the course of ischemic heart disease after percutaneous coronary intervention |
| title_full_unstemmed | Effect of ranolazine on the course of ischemic heart disease after percutaneous coronary intervention |
| title_short | Effect of ranolazine on the course of ischemic heart disease after percutaneous coronary intervention |
| title_sort | effect of ranolazine on the course of ischemic heart disease after percutaneous coronary intervention |
| topic | chronic ischemic heart disease percutaneous coronary intervention ranolazine |
| url | http://www.csic.com.ua/images/pdf/2020/4-2020/effect-ranolazine-course-ischemic-heart-disease-after-percutaneous-coronary-intervention.pdf |
| work_keys_str_mv | AT oayepanchintseva effectofranolazineonthecourseofischemicheartdiseaseafterpercutaneouscoronaryintervention AT ojzharinov effectofranolazineonthecourseofischemicheartdiseaseafterpercutaneouscoronaryintervention AT ívshklianka effectofranolazineonthecourseofischemicheartdiseaseafterpercutaneouscoronaryintervention |