Blue light-emitting diode phototherapy presents in vitro efficacy against distinct Leishmania species and is therapeutic against tegumentary leishmaniasis in BALB/c mice

Blue light-emitting diode phototherapy presents in vitro efficacy against distinct Leishmania species and is therapeutic against tegumentary leishmaniasis in BALB/c mice

The treatment of tegumentary leishmaniasis (TL) faces significant challenges, including drug toxicity, high costs, and the emergence of resistant strains. These limitations highlight the urgent need for novel antileishmanial agents and therapeutic strategies. This study evaluated blue light-emitting...

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Main Authors: Breno Luiz Pimenta, Daniela Pagliara Lage, Camila Simões de Freitas, Danniele Luciana Vale, Karolina Oliveira de Melo Falcão, Saulo Samuel Gonçalves Dias, Raquel Soares Bandeira Câmara, Isabela Amorim Gonçalves Pereira, Ana Luiza Silva, Lauro de Assis Duarte Júnior, Miguel Angel Chavez-Fumagalli, Rodrigo Fernando Bianchi, Eduardo Antonio Ferraz Coelho, André Talvani
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
blue LED phototherapy
tegumentary leishmaniasis
treatment
amphotericin B
immune response
antileishmanial activity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1554051/full
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