Correlation of MRI Visual Scales with Neuropsychological Profile in Mild Cognitive Impairment of Parkinson’s Disease
Few studies have evaluated magnetic resonance imaging (MRI) visual scales in Parkinson’s disease-Mild Cognitive Impairment (PD-MCI). We selected 79 PD patients and 92 controls (CO) to perform neurologic and neuropsychological evaluation. Brain MRI was performed to evaluate the following scales: Glob...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Parkinson's Disease |
| Online Access: | http://dx.doi.org/10.1155/2017/7380102 |
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| author | Luiz Felipe Vasconcellos João Santos Pereira Marcelo Adachi Denise Greca Manuela Cruz Ana Lara Malak Helenice Charchat-Fichman Mariana Spitz |
| author_facet | Luiz Felipe Vasconcellos João Santos Pereira Marcelo Adachi Denise Greca Manuela Cruz Ana Lara Malak Helenice Charchat-Fichman Mariana Spitz |
| author_sort | Luiz Felipe Vasconcellos |
| collection | DOAJ |
| description | Few studies have evaluated magnetic resonance imaging (MRI) visual scales in Parkinson’s disease-Mild Cognitive Impairment (PD-MCI). We selected 79 PD patients and 92 controls (CO) to perform neurologic and neuropsychological evaluation. Brain MRI was performed to evaluate the following scales: Global Cortical Atrophy (GCA), Fazekas, and medial temporal atrophy (MTA). The analysis revealed that both PD groups (amnestic and nonamnestic) showed worse performance on several tests when compared to CO. Memory, executive function, and attention impairment were more severe in amnestic PD-MCI group. Overall analysis of frequency of MRI visual scales by MCI subtype did not reveal any statistically significant result. Statistically significant inverse correlation was observed between GCA scale and Mini-Mental Status Examination (MMSE), Montreal Cognitive Assessment (MoCA), semantic verbal fluency, Stroop test, figure memory test, trail making test (TMT) B, and Rey Auditory Verbal Learning Test (RAVLT). The MTA scale correlated with Stroop test and Fazekas scale with figure memory test, digit span, and Stroop test according to the subgroup evaluated. Visual scales by MRI in MCI should be evaluated by cognitive domain and might be more useful in more severely impaired MCI or dementia patients. |
| format | Article |
| id | doaj-art-b5413ac1d8384733984d1a30941dcf46 |
| institution | Kabale University |
| issn | 2090-8083 2042-0080 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Parkinson's Disease |
| spelling | doaj-art-b5413ac1d8384733984d1a30941dcf462025-02-03T01:20:15ZengWileyParkinson's Disease2090-80832042-00802017-01-01201710.1155/2017/73801027380102Correlation of MRI Visual Scales with Neuropsychological Profile in Mild Cognitive Impairment of Parkinson’s DiseaseLuiz Felipe Vasconcellos0João Santos Pereira1Marcelo Adachi2Denise Greca3Manuela Cruz4Ana Lara Malak5Helenice Charchat-Fichman6Mariana Spitz7Movement Disorders Unit, Neurology Service, Pedro Ernesto University Hospital, State University of Rio de Janeiro, Rio de Janeiro, RJ, BrazilMovement Disorders Unit, Neurology Service, Pedro Ernesto University Hospital, State University of Rio de Janeiro, Rio de Janeiro, RJ, BrazilRadiology Department, Hospital Central da Polícia Militar, Rio de Janeiro, RJ, BrazilPsychology Department, Pontifical Catholic University of Rio de Janeiro (PUC-Rio), Rio de Janeiro, RJ, BrazilPsychology Department, Pontifical Catholic University of Rio de Janeiro (PUC-Rio), Rio de Janeiro, RJ, BrazilPsychology Department, Pontifical Catholic University of Rio de Janeiro (PUC-Rio), Rio de Janeiro, RJ, BrazilPsychology Department, Pontifical Catholic University of Rio de Janeiro (PUC-Rio), Rio de Janeiro, RJ, BrazilMovement Disorders Unit, Neurology Service, Pedro Ernesto University Hospital, State University of Rio de Janeiro, Rio de Janeiro, RJ, BrazilFew studies have evaluated magnetic resonance imaging (MRI) visual scales in Parkinson’s disease-Mild Cognitive Impairment (PD-MCI). We selected 79 PD patients and 92 controls (CO) to perform neurologic and neuropsychological evaluation. Brain MRI was performed to evaluate the following scales: Global Cortical Atrophy (GCA), Fazekas, and medial temporal atrophy (MTA). The analysis revealed that both PD groups (amnestic and nonamnestic) showed worse performance on several tests when compared to CO. Memory, executive function, and attention impairment were more severe in amnestic PD-MCI group. Overall analysis of frequency of MRI visual scales by MCI subtype did not reveal any statistically significant result. Statistically significant inverse correlation was observed between GCA scale and Mini-Mental Status Examination (MMSE), Montreal Cognitive Assessment (MoCA), semantic verbal fluency, Stroop test, figure memory test, trail making test (TMT) B, and Rey Auditory Verbal Learning Test (RAVLT). The MTA scale correlated with Stroop test and Fazekas scale with figure memory test, digit span, and Stroop test according to the subgroup evaluated. Visual scales by MRI in MCI should be evaluated by cognitive domain and might be more useful in more severely impaired MCI or dementia patients.http://dx.doi.org/10.1155/2017/7380102 |
| spellingShingle | Luiz Felipe Vasconcellos João Santos Pereira Marcelo Adachi Denise Greca Manuela Cruz Ana Lara Malak Helenice Charchat-Fichman Mariana Spitz Correlation of MRI Visual Scales with Neuropsychological Profile in Mild Cognitive Impairment of Parkinson’s Disease Parkinson's Disease |
| title | Correlation of MRI Visual Scales with Neuropsychological Profile in Mild Cognitive Impairment of Parkinson’s Disease |
| title_full | Correlation of MRI Visual Scales with Neuropsychological Profile in Mild Cognitive Impairment of Parkinson’s Disease |
| title_fullStr | Correlation of MRI Visual Scales with Neuropsychological Profile in Mild Cognitive Impairment of Parkinson’s Disease |
| title_full_unstemmed | Correlation of MRI Visual Scales with Neuropsychological Profile in Mild Cognitive Impairment of Parkinson’s Disease |
| title_short | Correlation of MRI Visual Scales with Neuropsychological Profile in Mild Cognitive Impairment of Parkinson’s Disease |
| title_sort | correlation of mri visual scales with neuropsychological profile in mild cognitive impairment of parkinson s disease |
| url | http://dx.doi.org/10.1155/2017/7380102 |
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