Quantitative Coronary Angiography Guidance for Drug‐Eluting Stent Implantation: A Narrative Review

ABSTRACT Background Percutaneous coronary intervention (PCI) using drug‐eluting stents is an established strategy for the treatment of significant obstructive coronary artery disease. Evidence supports that intravascular imaging‐guided PCI offers advantages over conventional angiography‐guided PCI,...

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Main Authors: Cheol Whan Lee, Pil Hyung Lee, Seung‐Whan Lee, Patrick W. Serruys
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Health Science Reports
Subjects:
Online Access:https://doi.org/10.1002/hsr2.70286
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author Cheol Whan Lee
Pil Hyung Lee
Seung‐Whan Lee
Patrick W. Serruys
author_facet Cheol Whan Lee
Pil Hyung Lee
Seung‐Whan Lee
Patrick W. Serruys
author_sort Cheol Whan Lee
collection DOAJ
description ABSTRACT Background Percutaneous coronary intervention (PCI) using drug‐eluting stents is an established strategy for the treatment of significant obstructive coronary artery disease. Evidence supports that intravascular imaging‐guided PCI offers advantages over conventional angiography‐guided PCI, though its use is limited, likely due to high costs. Angiography‐guided PCI relies on visual estimation, leading to inter‐ and intra‐observer variability and suboptimal outcomes. Quantitative coronary angiography (QCA) provides reliable information about vascular dimensions, overcoming these limitations. Poststenting postdilation with appropriately sized noncompliant balloons improves outcomes by increasing lumen area and reducing stent malapposition. Aims We investigated the procedural details of each modality used to guide PCI and assessed the utility of QCA‐guided PCI with routine postdilation when intravascular imaging is unavailable. Methods and Results A systematic search was conducted from inception to May 31, 2024, identifying nine randomized controlled trials (with over 500 patients) that compared outcomes of PCI guided by intravascular imaging versus conventional angiography or QCA. The findings indicate that intravascular imaging guidance significantly improves clinical outcomes compared to angiography guidance. Notably, QCA‐guided PCI with routine postdilation yielded outcomes comparable to those achieved with intravascular imaging‐guided PCI. Conclusions QCA‐guided PCI with routine postdilation may be a viable alternative for improving PCI outcomes, especially in settings where intravascular imaging is unavailable.
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spelling doaj-art-b534995507204f3e9e8a67c95405f2062025-08-20T02:51:12ZengWileyHealth Science Reports2398-88352024-12-01712n/an/a10.1002/hsr2.70286Quantitative Coronary Angiography Guidance for Drug‐Eluting Stent Implantation: A Narrative ReviewCheol Whan Lee0Pil Hyung Lee1Seung‐Whan Lee2Patrick W. Serruys3Division of Cardiology Heart Institute, Asan Medical Centre, University of Ulsan College of Medicine Seoul South KoreaDivision of Cardiology Heart Institute, Asan Medical Centre, University of Ulsan College of Medicine Seoul South KoreaDivision of Cardiology Heart Institute, Asan Medical Centre, University of Ulsan College of Medicine Seoul South KoreaCORRIB Research Centre for Advanced Imaging and Core Lab University of Galway Galway IrelandABSTRACT Background Percutaneous coronary intervention (PCI) using drug‐eluting stents is an established strategy for the treatment of significant obstructive coronary artery disease. Evidence supports that intravascular imaging‐guided PCI offers advantages over conventional angiography‐guided PCI, though its use is limited, likely due to high costs. Angiography‐guided PCI relies on visual estimation, leading to inter‐ and intra‐observer variability and suboptimal outcomes. Quantitative coronary angiography (QCA) provides reliable information about vascular dimensions, overcoming these limitations. Poststenting postdilation with appropriately sized noncompliant balloons improves outcomes by increasing lumen area and reducing stent malapposition. Aims We investigated the procedural details of each modality used to guide PCI and assessed the utility of QCA‐guided PCI with routine postdilation when intravascular imaging is unavailable. Methods and Results A systematic search was conducted from inception to May 31, 2024, identifying nine randomized controlled trials (with over 500 patients) that compared outcomes of PCI guided by intravascular imaging versus conventional angiography or QCA. The findings indicate that intravascular imaging guidance significantly improves clinical outcomes compared to angiography guidance. Notably, QCA‐guided PCI with routine postdilation yielded outcomes comparable to those achieved with intravascular imaging‐guided PCI. Conclusions QCA‐guided PCI with routine postdilation may be a viable alternative for improving PCI outcomes, especially in settings where intravascular imaging is unavailable.https://doi.org/10.1002/hsr2.70286intravascular imagingpercutaneous coronary interventionquantitative coronary angiography
spellingShingle Cheol Whan Lee
Pil Hyung Lee
Seung‐Whan Lee
Patrick W. Serruys
Quantitative Coronary Angiography Guidance for Drug‐Eluting Stent Implantation: A Narrative Review
Health Science Reports
intravascular imaging
percutaneous coronary intervention
quantitative coronary angiography
title Quantitative Coronary Angiography Guidance for Drug‐Eluting Stent Implantation: A Narrative Review
title_full Quantitative Coronary Angiography Guidance for Drug‐Eluting Stent Implantation: A Narrative Review
title_fullStr Quantitative Coronary Angiography Guidance for Drug‐Eluting Stent Implantation: A Narrative Review
title_full_unstemmed Quantitative Coronary Angiography Guidance for Drug‐Eluting Stent Implantation: A Narrative Review
title_short Quantitative Coronary Angiography Guidance for Drug‐Eluting Stent Implantation: A Narrative Review
title_sort quantitative coronary angiography guidance for drug eluting stent implantation a narrative review
topic intravascular imaging
percutaneous coronary intervention
quantitative coronary angiography
url https://doi.org/10.1002/hsr2.70286
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AT pilhyunglee quantitativecoronaryangiographyguidancefordrugelutingstentimplantationanarrativereview
AT seungwhanlee quantitativecoronaryangiographyguidancefordrugelutingstentimplantationanarrativereview
AT patrickwserruys quantitativecoronaryangiographyguidancefordrugelutingstentimplantationanarrativereview