Cymbopogon citratus Essential Oil Protects Tubular Renal Cells against Ischemia/Reoxygenation Injury - Involvement Nrf2/Keap1 Pathway

Cymbopogon citratus Essential Oil Protects Tubular Renal Cells against Ischemia/Reoxygenation Injury - Involvement Nrf2/Keap1 Pathway

Abstract Ischemia and reoxygenation (I/R) cause acute kidney injury with progression related to oxidative damage, mitochondrial dysfunction and cell death. Nrf2-Keap1 pathway is involved in this process. Cymbopogon citratus, used in popular medicine, is a promising source of bioactive antioxidant co...

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Main Authors: Duaran Lopes de Sousa, Mary Anne Medeiros Bandeira, Igor Lima Soares, Bruna Ribeiro Duque, Mac Dionys Rodrigues da Costa, Glautemberg de Almeida Viana, Emanuel Paula Magalhães, Ramon Róseo Paula Pessoa Bezerra de Menezes, Tiago Lima Sampaio, Márcia Machado Marinho, Alice Maria Costa Martins
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2025-08-01
Series:Brazilian Archives of Biology and Technology
Subjects:
citral
KEAP-1
acute kidney injury
antioxidants.
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132025000101406&lng=en&tlng=en
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