Association between daily alcohol intake and hypertension prevalence: evidence from the 2007–2018 NHANES database
Abstract Background Hypertension is a major public health issue globally, affecting hundreds of millions of people. Although the association between alcohol consumption and hypertension has been widely demonstrated, uncertainties remain regarding the dose-response relationship, potential confounding...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
|
| Series: | BMC Cardiovascular Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12872-025-05035-6 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849334027566186496 |
|---|---|
| author | Xiao-Feng Fan Hong Xie Wen-Huan Shuai Gui-You Zhong |
| author_facet | Xiao-Feng Fan Hong Xie Wen-Huan Shuai Gui-You Zhong |
| author_sort | Xiao-Feng Fan |
| collection | DOAJ |
| description | Abstract Background Hypertension is a major public health issue globally, affecting hundreds of millions of people. Although the association between alcohol consumption and hypertension has been widely demonstrated, uncertainties remain regarding the dose-response relationship, potential confounding factors, and population-specific differences. Methods Data from NHANES participants aged 20 and above from 2007 to 2018 were analyzed. A weighted multivariate logistic regression model assessed the association between daily alcohol intake and hypertension prevalence, calculating adjusted odds ratios (ORs) and 95% confidence intervals (CIs). Restricted cubic splines (RCS) examined the potential non-linear association. Subgroup analyses evaluated interaction effects across demographic variables to identify differences in the alcohol-hypertension association among populations. Results This study included 30,127 eligible participants, representing 228,198,440 individuals in the United States population after weighting. In the fully adjusted Model 3, a significant positive association was observed between daily alcohol intake and hypertension prevalence (OR: 1.007, 95% CI: 1.005–1.009; P < 0.001). Compared to the abstainers group (0 g/d), participants in the very heavy consumers group (> 40 g/d) had a significantly higher prevalence of hypertension (OR: 1.873, 95% CI: 1.585–2.213; P < 0.001). RCS analysis further confirmed the positive association between daily alcohol intake and hypertension prevalence, with no significant non-linearity detected. In the subgroup analysis, a significant interaction was detected in the racial/ethnic subgroup (P for interaction < 0.05). Conclusion A significant association exists between very heavy alcohol consumers (> 40 g/d) and an increased prevalence of hypertension. These findings underscore the importance of including alcohol intake assessments in hypertension management and prevention strategies. Further research is needed to explore the causal association between alcohol intake and hypertension and to investigate its potential biological mechanisms. |
| format | Article |
| id | doaj-art-b529fec5240f47288f347fa03ceee001 |
| institution | Kabale University |
| issn | 1471-2261 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj-art-b529fec5240f47288f347fa03ceee0012025-08-20T03:45:40ZengBMCBMC Cardiovascular Disorders1471-22612025-08-0125111210.1186/s12872-025-05035-6Association between daily alcohol intake and hypertension prevalence: evidence from the 2007–2018 NHANES databaseXiao-Feng Fan0Hong Xie1Wen-Huan Shuai2Gui-You Zhong3Department of Cardiology, Zigong Fourth People’s HospitalDepartment of General Medicine, Zigong Fourth People’s HospitalDepartment of Cardiology, Zigong Fourth People’s HospitalDepartment of Cardiology, Zigong Fourth People’s HospitalAbstract Background Hypertension is a major public health issue globally, affecting hundreds of millions of people. Although the association between alcohol consumption and hypertension has been widely demonstrated, uncertainties remain regarding the dose-response relationship, potential confounding factors, and population-specific differences. Methods Data from NHANES participants aged 20 and above from 2007 to 2018 were analyzed. A weighted multivariate logistic regression model assessed the association between daily alcohol intake and hypertension prevalence, calculating adjusted odds ratios (ORs) and 95% confidence intervals (CIs). Restricted cubic splines (RCS) examined the potential non-linear association. Subgroup analyses evaluated interaction effects across demographic variables to identify differences in the alcohol-hypertension association among populations. Results This study included 30,127 eligible participants, representing 228,198,440 individuals in the United States population after weighting. In the fully adjusted Model 3, a significant positive association was observed between daily alcohol intake and hypertension prevalence (OR: 1.007, 95% CI: 1.005–1.009; P < 0.001). Compared to the abstainers group (0 g/d), participants in the very heavy consumers group (> 40 g/d) had a significantly higher prevalence of hypertension (OR: 1.873, 95% CI: 1.585–2.213; P < 0.001). RCS analysis further confirmed the positive association between daily alcohol intake and hypertension prevalence, with no significant non-linearity detected. In the subgroup analysis, a significant interaction was detected in the racial/ethnic subgroup (P for interaction < 0.05). Conclusion A significant association exists between very heavy alcohol consumers (> 40 g/d) and an increased prevalence of hypertension. These findings underscore the importance of including alcohol intake assessments in hypertension management and prevention strategies. Further research is needed to explore the causal association between alcohol intake and hypertension and to investigate its potential biological mechanisms.https://doi.org/10.1186/s12872-025-05035-6HypertensionAlcohol intakeNHANESRisk factorsEpidemiology |
| spellingShingle | Xiao-Feng Fan Hong Xie Wen-Huan Shuai Gui-You Zhong Association between daily alcohol intake and hypertension prevalence: evidence from the 2007–2018 NHANES database BMC Cardiovascular Disorders Hypertension Alcohol intake NHANES Risk factors Epidemiology |
| title | Association between daily alcohol intake and hypertension prevalence: evidence from the 2007–2018 NHANES database |
| title_full | Association between daily alcohol intake and hypertension prevalence: evidence from the 2007–2018 NHANES database |
| title_fullStr | Association between daily alcohol intake and hypertension prevalence: evidence from the 2007–2018 NHANES database |
| title_full_unstemmed | Association between daily alcohol intake and hypertension prevalence: evidence from the 2007–2018 NHANES database |
| title_short | Association between daily alcohol intake and hypertension prevalence: evidence from the 2007–2018 NHANES database |
| title_sort | association between daily alcohol intake and hypertension prevalence evidence from the 2007 2018 nhanes database |
| topic | Hypertension Alcohol intake NHANES Risk factors Epidemiology |
| url | https://doi.org/10.1186/s12872-025-05035-6 |
| work_keys_str_mv | AT xiaofengfan associationbetweendailyalcoholintakeandhypertensionprevalenceevidencefromthe20072018nhanesdatabase AT hongxie associationbetweendailyalcoholintakeandhypertensionprevalenceevidencefromthe20072018nhanesdatabase AT wenhuanshuai associationbetweendailyalcoholintakeandhypertensionprevalenceevidencefromthe20072018nhanesdatabase AT guiyouzhong associationbetweendailyalcoholintakeandhypertensionprevalenceevidencefromthe20072018nhanesdatabase |