Quantitative response assessment of combined immunotherapy in a murine melanoma model using multiparametric MRI

Abstract Background We assessed immunotherapy response in a murine melanoma model using multiparametric magnetic resonance imaging (mpMRI) features with ex vivo immunohistochemical validation. Methods Murine melanoma cells (B16-F10) were inoculated into the subcutaneous flank of n = 28 C57BL/6 mice...

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Main Authors: Maurice M. Heimer, Amra Cimic, Sandra Kloiber-Langhorst, Melissa J. Antons, Jennifer Stueckl, Heidrun Hirner-Eppeneder, Wolfgang G. Kunz, Olaf Dietrich, Jens Ricke, Felix L. Herr, Clemens C. Cyran
Format: Article
Language:English
Published: SpringerOpen 2025-06-01
Series:European Radiology Experimental
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Online Access:https://doi.org/10.1186/s41747-025-00597-8
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