Herpetic meningomyelitis: An exceptional presentation of herpes simplex virus
Herpetic meningomyelitis is an inflammation of the meninges and spinal cord caused by Herpes simplex virus type 2 (HSV-2). It typically occurs during HSV-2 reactivation, with or without immunosuppressive factors. We report a rare case of herpetic meningomyelitis in a 41-year-old HIV-positive patient...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-07-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043325002997 |
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| author | Sara Khayer Imane Sellam Brahim Abouhali Mouna ELfane |
| author_facet | Sara Khayer Imane Sellam Brahim Abouhali Mouna ELfane |
| author_sort | Sara Khayer |
| collection | DOAJ |
| description | Herpetic meningomyelitis is an inflammation of the meninges and spinal cord caused by Herpes simplex virus type 2 (HSV-2). It typically occurs during HSV-2 reactivation, with or without immunosuppressive factors. We report a rare case of herpetic meningomyelitis in a 41-year-old HIV-positive patient, presenting with rapidly progressive ascending paraparesis. Diagnosis was confirmed by cerebrospinal fluid (CSF) multiplex PCR, revealing HSV-2, and spinal cord MRI showing central hyperintensities. The patient was treated with intravenous acyclovir and corticosteroids, leading to significant neurological recovery. This case highlights the importance of early recognition and management of this rare neurological complication of HSV-2. |
| format | Article |
| id | doaj-art-b5120fb925a146ab83d1d8b818a4116a |
| institution | OA Journals |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-b5120fb925a146ab83d1d8b818a4116a2025-08-20T01:50:01ZengElsevierRadiology Case Reports1930-04332025-07-012073625362710.1016/j.radcr.2025.04.001Herpetic meningomyelitis: An exceptional presentation of herpes simplex virusSara Khayer0Imane Sellam1Brahim Abouhali2Mouna ELfane3Corresponding author.; Infectious Diseases Department, Hassan II Agadir Regional Hospital, Souss Massa University Hospital, UIZ, Agadir, MoroccoInfectious Diseases Department, Hassan II Agadir Regional Hospital, Souss Massa University Hospital, UIZ, Agadir, MoroccoInfectious Diseases Department, Hassan II Agadir Regional Hospital, Souss Massa University Hospital, UIZ, Agadir, MoroccoInfectious Diseases Department, Hassan II Agadir Regional Hospital, Souss Massa University Hospital, UIZ, Agadir, MoroccoHerpetic meningomyelitis is an inflammation of the meninges and spinal cord caused by Herpes simplex virus type 2 (HSV-2). It typically occurs during HSV-2 reactivation, with or without immunosuppressive factors. We report a rare case of herpetic meningomyelitis in a 41-year-old HIV-positive patient, presenting with rapidly progressive ascending paraparesis. Diagnosis was confirmed by cerebrospinal fluid (CSF) multiplex PCR, revealing HSV-2, and spinal cord MRI showing central hyperintensities. The patient was treated with intravenous acyclovir and corticosteroids, leading to significant neurological recovery. This case highlights the importance of early recognition and management of this rare neurological complication of HSV-2.http://www.sciencedirect.com/science/article/pii/S1930043325002997MeningitisMyelitisHSV-2HIVNeurological complications |
| spellingShingle | Sara Khayer Imane Sellam Brahim Abouhali Mouna ELfane Herpetic meningomyelitis: An exceptional presentation of herpes simplex virus Radiology Case Reports Meningitis Myelitis HSV-2 HIV Neurological complications |
| title | Herpetic meningomyelitis: An exceptional presentation of herpes simplex virus |
| title_full | Herpetic meningomyelitis: An exceptional presentation of herpes simplex virus |
| title_fullStr | Herpetic meningomyelitis: An exceptional presentation of herpes simplex virus |
| title_full_unstemmed | Herpetic meningomyelitis: An exceptional presentation of herpes simplex virus |
| title_short | Herpetic meningomyelitis: An exceptional presentation of herpes simplex virus |
| title_sort | herpetic meningomyelitis an exceptional presentation of herpes simplex virus |
| topic | Meningitis Myelitis HSV-2 HIV Neurological complications |
| url | http://www.sciencedirect.com/science/article/pii/S1930043325002997 |
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