Diagnosis and Management of Retrograde Cricopharyngeal Dysfunction: A Systematic Review
Abstract Objective Retrograde cricopharyngeal dysfunction (R‐CPD) is a syndrome with rapidly increasing awareness since being first described in March 2019. As such, few cases of R‐CPD are currently reported in the literature. The goal of this study is to provide a comprehensive systematic review of...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-10-01
|
| Series: | OTO Open |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/oto2.70014 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Abstract Objective Retrograde cricopharyngeal dysfunction (R‐CPD) is a syndrome with rapidly increasing awareness since being first described in March 2019. As such, few cases of R‐CPD are currently reported in the literature. The goal of this study is to provide a comprehensive systematic review of the available literature on R‐CPD, including patient characteristics, diagnosis, and management. Data Sources PubMed, Scopus, EMBASE. Review Methods A systematic review of the available English literature was conducted using the data sources PubMed, Scopus, and EMBASE. Studies with original data of patients experiencing classic symptoms of R‐CPD were included. Independent abstract screening followed by full‐text screening was performed to assess study eligibility. Data extraction of patient demographics, symptoms, treatment, and follow‐up were subsequently performed. Results Common presentations of R‐CPD include abelchia (100%), abdominal bloating (83%), and gurgling noises (75%). 554 (86.9%) patients had improved symptoms after initial treatment with BTX. The most common initial dose was 50 units in 204 (37.3%) patients. Subsequent BTX injections resolved symptoms in 40 (80%) patients. Six patients ultimately received CP myotomy for recurrent symptoms, resulting in long‐term resolution in 4 (67%) patients. Conclusion R‐CPD is a newly recognized syndrome with effective treatment options including botulinum toxin injections and cricopharyngeal myotomy, where appropriate. Diagnostic modalities including esophageal manometry may aid in the initial work up of R‐CPD, however further studies are required to assess its diagnostic utility. |
|---|---|
| ISSN: | 2473-974X |