The influence of succinate-containing drugs on physical performance and recovery after exercise

An assessment of the influence of 2-ethyl-6-methyl-3-hydroxypyridine succinate (Mexidol) on the physical performance of small laboratory animals and recovery after exercise was made. As a result, it was found that a single application of Mexidol increases the endurance of animals, estimated as maxim...

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Main Authors: S. V. Radko, A. D. Dulepov
Format: Article
Language:Russian
Published: LLC “Publisher OKI” 2019-01-01
Series:Фармакокинетика и Фармакодинамика
Subjects:
Online Access:https://www.pharmacokinetica.ru/jour/article/view/79
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author S. V. Radko
A. D. Dulepov
author_facet S. V. Radko
A. D. Dulepov
author_sort S. V. Radko
collection DOAJ
description An assessment of the influence of 2-ethyl-6-methyl-3-hydroxypyridine succinate (Mexidol) on the physical performance of small laboratory animals and recovery after exercise was made. As a result, it was found that a single application of Mexidol increases the endurance of animals, estimated as maximum swimming time, 1.57 times. With the course of the drug, there was a tendency to improve performance with access to the plateau after the 3rd week, similar to the comparative drug - bis {2 - [(2E) -4-hydroxy-4-oxobut-2-enyloxy] -N, N-diethylethanaminium} butanedioate.
format Article
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institution Kabale University
issn 2587-7836
2686-8830
language Russian
publishDate 2019-01-01
publisher LLC “Publisher OKI”
record_format Article
series Фармакокинетика и Фармакодинамика
spelling doaj-art-b4f5db5b394d4a539ce472bdd24b6cc52025-08-20T03:42:31ZrusLLC “Publisher OKI”Фармакокинетика и Фармакодинамика2587-78362686-88302019-01-01013510.24411/2587-7836-2019-1003278The influence of succinate-containing drugs on physical performance and recovery after exerciseS. V. Radko0A. D. Dulepov1Saint Petersburg State Chemical Pharmaceutical University (SPCPU)Saint Petersburg State Chemical Pharmaceutical University (SPCPU)An assessment of the influence of 2-ethyl-6-methyl-3-hydroxypyridine succinate (Mexidol) on the physical performance of small laboratory animals and recovery after exercise was made. As a result, it was found that a single application of Mexidol increases the endurance of animals, estimated as maximum swimming time, 1.57 times. With the course of the drug, there was a tendency to improve performance with access to the plateau after the 3rd week, similar to the comparative drug - bis {2 - [(2E) -4-hydroxy-4-oxobut-2-enyloxy] -N, N-diethylethanaminium} butanedioate.https://www.pharmacokinetica.ru/jour/article/view/79работоспособностьэтилметилгидроксипиридина сукцинатвынужденное плаваниемексидолphysical efficiencysuccinateethylmethylhydroxypyridine succinateforsed swimmin
spellingShingle S. V. Radko
A. D. Dulepov
The influence of succinate-containing drugs on physical performance and recovery after exercise
Фармакокинетика и Фармакодинамика
работоспособность
этилметилгидроксипиридина сукцинат
вынужденное плавание
мексидол
physical efficiency
succinate
ethylmethylhydroxypyridine succinate
forsed swimmin
title The influence of succinate-containing drugs on physical performance and recovery after exercise
title_full The influence of succinate-containing drugs on physical performance and recovery after exercise
title_fullStr The influence of succinate-containing drugs on physical performance and recovery after exercise
title_full_unstemmed The influence of succinate-containing drugs on physical performance and recovery after exercise
title_short The influence of succinate-containing drugs on physical performance and recovery after exercise
title_sort influence of succinate containing drugs on physical performance and recovery after exercise
topic работоспособность
этилметилгидроксипиридина сукцинат
вынужденное плавание
мексидол
physical efficiency
succinate
ethylmethylhydroxypyridine succinate
forsed swimmin
url https://www.pharmacokinetica.ru/jour/article/view/79
work_keys_str_mv AT svradko theinfluenceofsuccinatecontainingdrugsonphysicalperformanceandrecoveryafterexercise
AT addulepov theinfluenceofsuccinatecontainingdrugsonphysicalperformanceandrecoveryafterexercise
AT svradko influenceofsuccinatecontainingdrugsonphysicalperformanceandrecoveryafterexercise
AT addulepov influenceofsuccinatecontainingdrugsonphysicalperformanceandrecoveryafterexercise