The influence of succinate-containing drugs on physical performance and recovery after exercise

An assessment of the influence of 2-ethyl-6-methyl-3-hydroxypyridine succinate (Mexidol) on the physical performance of small laboratory animals and recovery after exercise was made. As a result, it was found that a single application of Mexidol increases the endurance of animals, estimated as maxim...

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Bibliographic Details
Main Authors: S. V. Radko, A. D. Dulepov
Format: Article
Language:Russian
Published: LLC “Publisher OKI” 2019-01-01
Series:Фармакокинетика и Фармакодинамика
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Online Access:https://www.pharmacokinetica.ru/jour/article/view/79
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Summary:An assessment of the influence of 2-ethyl-6-methyl-3-hydroxypyridine succinate (Mexidol) on the physical performance of small laboratory animals and recovery after exercise was made. As a result, it was found that a single application of Mexidol increases the endurance of animals, estimated as maximum swimming time, 1.57 times. With the course of the drug, there was a tendency to improve performance with access to the plateau after the 3rd week, similar to the comparative drug - bis {2 - [(2E) -4-hydroxy-4-oxobut-2-enyloxy] -N, N-diethylethanaminium} butanedioate.
ISSN:2587-7836
2686-8830