Simulation of a Custom-Made Temporomandibular Joint—An Academic View on an Industrial Workflow
Temporomandibular joint replacement is a critical intervention for severe temporomandibular joint disorders, enhancing pain levels, jaw function and overall quality of life. In this study, we compare two finite element method-based simulation workflows from both academic and industrial perspectives,...
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MDPI AG
2025-05-01
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| Series: | Bioengineering |
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| Online Access: | https://www.mdpi.com/2306-5354/12/5/545 |
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| author | Annchristin Andres Kerstin Wickert Elena Gneiting Franziska Binmoeller Stefan Diebels Michael Roland |
| author_facet | Annchristin Andres Kerstin Wickert Elena Gneiting Franziska Binmoeller Stefan Diebels Michael Roland |
| author_sort | Annchristin Andres |
| collection | DOAJ |
| description | Temporomandibular joint replacement is a critical intervention for severe temporomandibular joint disorders, enhancing pain levels, jaw function and overall quality of life. In this study, we compare two finite element method-based simulation workflows from both academic and industrial perspectives, focusing on a patient-specific case involving a custom-made temporomandibular joint prosthesis. Using computed tomography data and computer-aided design data, we generated different 3D models and performed mechanical testing, including wear and static compression tests. Our results indicate that the academic workflow, which is retrospective, purely image-based and applied post-operatively, produced peak stress values within 9–20% of those obtained from the industrial workflow. The industrial workflow is prospective, pre-operative, computer-aided design-based and guided by stringent regulatory standards and approval protocols. Observed differences between workflows were attributed primarily to distinct modelling assumptions, simplifications and constraints inherent in each method. To explicitly quantify these differences, multiple additional models were generated within the academic workflow using partial data from the industrial process, revealing specific sources of variation in stress distribution and implant performance. The findings underscore the potential of patient-specific simulations not only to refine temporomandibular joint prosthesis design and enhance patient outcomes, but also to highlight the interplay between academic research methodologies and industrial standards in the development of medical devices. |
| format | Article |
| id | doaj-art-b4f2f0fe27274d15b4e17bcd82810039 |
| institution | DOAJ |
| issn | 2306-5354 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Bioengineering |
| spelling | doaj-art-b4f2f0fe27274d15b4e17bcd828100392025-08-20T03:14:40ZengMDPI AGBioengineering2306-53542025-05-0112554510.3390/bioengineering12050545Simulation of a Custom-Made Temporomandibular Joint—An Academic View on an Industrial WorkflowAnnchristin Andres0Kerstin Wickert1Elena Gneiting2Franziska Binmoeller3Stefan Diebels4Michael Roland5Applied Mechanics, Saarland University, Campus A4 2, 1. OG, 66123 Saarbrücken, GermanyApplied Mechanics, Saarland University, Campus A4 2, 1. OG, 66123 Saarbrücken, GermanyKLS Martin SE & Co. KG, 78532 Tuttlingen, GermanyKLS Martin SE & Co. KG, 78532 Tuttlingen, GermanyApplied Mechanics, Saarland University, Campus A4 2, 1. OG, 66123 Saarbrücken, GermanyApplied Mechanics, Saarland University, Campus A4 2, 1. OG, 66123 Saarbrücken, GermanyTemporomandibular joint replacement is a critical intervention for severe temporomandibular joint disorders, enhancing pain levels, jaw function and overall quality of life. In this study, we compare two finite element method-based simulation workflows from both academic and industrial perspectives, focusing on a patient-specific case involving a custom-made temporomandibular joint prosthesis. Using computed tomography data and computer-aided design data, we generated different 3D models and performed mechanical testing, including wear and static compression tests. Our results indicate that the academic workflow, which is retrospective, purely image-based and applied post-operatively, produced peak stress values within 9–20% of those obtained from the industrial workflow. The industrial workflow is prospective, pre-operative, computer-aided design-based and guided by stringent regulatory standards and approval protocols. Observed differences between workflows were attributed primarily to distinct modelling assumptions, simplifications and constraints inherent in each method. To explicitly quantify these differences, multiple additional models were generated within the academic workflow using partial data from the industrial process, revealing specific sources of variation in stress distribution and implant performance. The findings underscore the potential of patient-specific simulations not only to refine temporomandibular joint prosthesis design and enhance patient outcomes, but also to highlight the interplay between academic research methodologies and industrial standards in the development of medical devices.https://www.mdpi.com/2306-5354/12/5/545temporomandibular joint replacementfinite element analysisbiomechanicscustom-made prothesisexperimental prothesis testingpatient-specific model generation |
| spellingShingle | Annchristin Andres Kerstin Wickert Elena Gneiting Franziska Binmoeller Stefan Diebels Michael Roland Simulation of a Custom-Made Temporomandibular Joint—An Academic View on an Industrial Workflow Bioengineering temporomandibular joint replacement finite element analysis biomechanics custom-made prothesis experimental prothesis testing patient-specific model generation |
| title | Simulation of a Custom-Made Temporomandibular Joint—An Academic View on an Industrial Workflow |
| title_full | Simulation of a Custom-Made Temporomandibular Joint—An Academic View on an Industrial Workflow |
| title_fullStr | Simulation of a Custom-Made Temporomandibular Joint—An Academic View on an Industrial Workflow |
| title_full_unstemmed | Simulation of a Custom-Made Temporomandibular Joint—An Academic View on an Industrial Workflow |
| title_short | Simulation of a Custom-Made Temporomandibular Joint—An Academic View on an Industrial Workflow |
| title_sort | simulation of a custom made temporomandibular joint an academic view on an industrial workflow |
| topic | temporomandibular joint replacement finite element analysis biomechanics custom-made prothesis experimental prothesis testing patient-specific model generation |
| url | https://www.mdpi.com/2306-5354/12/5/545 |
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